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539743 InhibitorSelect™ 384-Well Protein Kinase Inhibitor Library I - Calbiochem

InhibitorSelect™ 384-Well Protein Kinase Inhibitor Library I contains 160 well-characterized, cell-permeable, potent, reversible protein kinase inhibitors; the majority of which are ATP-competitive.

SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
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      Übersicht

      Replacement Information
      Description
      Overview

      This product has been discontinued.



      The InhibitorSelect™ 384-Well Protein Kinase Inhibitor Library I consists of 160 well-characterized, cell-permeable, potent, and reversible protein kinase inhibitors; the majority of which are ATP-competitive. They are supplied in a convenient 384-well plate format at a concentration of 10 mM in DMSO. The inhibitors in this library will be useful for target identification in drug discovery, biochemical pathway analysis, high-throughput kinase profiling, and other pharmaceutical-related applications.
      Supplied with a CD containing comprehensive documentation for each inhibitor. Please contact technical service for further details.

      Download a list of all inhibitors of library I, including a comprehensive data set.
      Catalogue Number539743
      Brand Family Calbiochem®
      Application Data

      **Total higher than 160, as some inhibitors target kinases in other branches as well. TK: Tyrosine Kinase Group TKL: Tyrosine Kinase-Like Group AGC: PKA, PKG, and PKC Containing Group CMGC: Cdk, MAPK, GSK3, and CLK Containing Group CAMK: Ca2+/Calmodulin Dependent Protein Kinases CK: Casein Protein Kinases STE: Yeast Sterile Protein Kinases
      References
      Product Information
      Form384-well plate
      FormulationAll of the inhibitors, except for one, are supplied at a concentration of 10 mM in DMSO (25 µl/well).
      Hygroscopic Hygroscopic
      Applications
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Regulatory Review
      Storage ≤ -70°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsPlease note that the contents of the resealable bag have been purged under nitrogen. Open the bubble pouch and the resealable bag. Remove the plate from the bag, and let it thaw at room temperature. Remove the lid and mat gently. For long-term storage, tightly reseal with the mat, place in the resealable bag and purge with an inert gas. Store at -70°C in an upright position. Minimize freeze/thaw cycles. Product is stable for up to one year after receipt.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      539743 0

      Documentation

      InhibitorSelect™ 384-Well Protein Kinase Inhibitor Library I - Calbiochem SDB

      Titel

      Sicherheitsdatenblatt (SDB) 

      InhibitorSelect™ 384-Well Protein Kinase Inhibitor Library I - Calbiochem Analysenzertifikate

      TitelChargennummer
      539743

      Datenblatt

      Titel
      Reprogramming Cell Fate and Function Novel Strategies for iPSC Generation, Characterization, and Differentiation

      Literaturstellen

      Titel
    • Anastassiadis, T., et al. 2011. Nature Biotech. 29, 1039.
    • Cohen, T., et al. 2012. Biochem. J. in press.
    • Elkaim, J., 2012. Biochem. J. in press.
    • Baxter, B.K., et al. 2011. ACS Chem. Biol. in press.
    • Lanier, m. et al. 2011. J. Med. Chem. DOI: 10.1021/jm2010223.
    • Wong, S.W., et al. 2010. Breast Cancer Res. Treat. in press.
    • Chou, T-F. and Deshaies, R.J., 2011. JBC Papers in Press.
    • Li, T., et al. 2010. Anal. Chem. 82, 3067.
    • Johnson, J.L., et al. 2009.BMC Microbiol. 9, 218.
      		•
      Datenblatt

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision11-September-2012 JSW
      Application Data

      **Total higher than 160, as some inhibitors target kinases in other branches as well. TK: Tyrosine Kinase Group TKL: Tyrosine Kinase-Like Group AGC: PKA, PKG, and PKC Containing Group CMGC: Cdk, MAPK, GSK3, and CLK Containing Group CAMK: Ca2+/Calmodulin Dependent Protein Kinases CK: Casein Protein Kinases STE: Yeast Sterile Protein Kinases
      DescriptionThe InhibitorSelect™ 384-Well Protein Kinase Inhibitor Library I consists of 160 well-characterized, cell-permeable, potent, and reversible protein kinase inhibitors; the majority of which are ATP-competitive. They are supplied in a convenient 384-well plate format at a concentration of 10 mM in DMSO. The inhibitors in this library will be useful for target identification in drug discovery, biochemical pathway analysis, high-throughput kinase profiling, and other pharmaceutical-related applications. Supplied with a CD containing comprehensive documentation for each inhibitor. Please contact technical service for further details.
      Form384-well plate
      FormulationAll of the inhibitors, except for one, are supplied at a concentration of 10 mM in DMSO (25 µl/well).
      Intert gas (Yes/No) Packaged under inert gas
      Storage Protect from light
      Avoid freeze/thaw
      ≤ -70°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsPlease note that the contents of the resealable bag have been purged under nitrogen. Open the bubble pouch and the resealable bag. Remove the plate from the bag, and let it thaw at room temperature. Remove the lid and mat gently. For long-term storage, tightly reseal with the mat, place in the resealable bag and purge with an inert gas. Store at -70°C in an upright position. Minimize freeze/thaw cycles. Product is stable for up to one year after receipt.
      Toxicity Regulatory Review
      Citation
    • Anastassiadis, T., et al. 2011. Nature Biotech. 29, 1039.
    • Cohen, T., et al. 2012. Biochem. J. in press.
    • Elkaim, J., 2012. Biochem. J. in press.
    • Baxter, B.K., et al. 2011. ACS Chem. Biol. in press.
    • Lanier, m. et al. 2011. J. Med. Chem. DOI: 10.1021/jm2010223.
    • Wong, S.W., et al. 2010. Breast Cancer Res. Treat. in press.
    • Chou, T-F. and Deshaies, R.J., 2011. JBC Papers in Press.
    • Li, T., et al. 2010. Anal. Chem. 82, 3067.
    • Johnson, J.L., et al. 2009.BMC Microbiol. 9, 218.
      		•