584223 Sigma-AldrichInSolution™ Tetrahydrouridine - CAS 18771-50-1 - Calbiochem
Tetrahydrouridine is a potent competitive inhibitor of cytidine deaminase.
More>> Tetrahydrouridine is a potent competitive inhibitor of cytidine deaminase. Less<<Synonyme: 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-hydroxytetrahydropyrimidin-2(1H)-one, dihydrate, THU, H4U
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Übersicht
Replacement Information |
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Key Spec Table
CAS # | Empirical Formula |
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18771-50-1 | C₉H₁₆N₂O₆ • 2H₂O |
Preis & Verfügbarkeit
Bestellnummer | Verfügbarkeit | Verpackung | St./Pkg. | Preis | Menge | |
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584223-25MG |
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Glasflasche | 25 mg |
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Description | |
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Overview | A potent competitive inhibitor of cytidine deaminase. Used in combination with cytosine arabinoside (Ara-C) to assess the anti-leukemic activity and anti-tumor activity of Ara-C in in vitro studies. The solid form of this compound (Cat. No. 584222) is also available. |
Catalogue Number | 584223 |
Brand Family | Calbiochem® |
Synonyms | 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-hydroxytetrahydropyrimidin-2(1H)-one, dihydrate, THU, H4U |
Product Information | |
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CAS number | 18771-50-1 |
Form | Liquid |
Formulation | A 100 mM (25 mg/879 µL) solution of Tetrahydrouridine (Cat. No. 584222) in H₂O. |
Hill Formula | C₉H₁₆N₂O₆ • 2H₂O |
Reversible | Y |
Structure formula Image | |
Quality Level | MQ100 |
Applications |
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Biological Information | |
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Primary Target | cytidine deaminase |
Purity | ≥90% by TLC |
Physicochemical Information | |
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Cell permeable | Y |
Dimensions |
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Materials Information |
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Safety Information according to GHS |
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Safety Information |
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Product Usage Statements |
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Packaging Information | |
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Packaged under inert gas | Packaged under inert gas |
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Supplemental Information |
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Specifications |
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Global Trade Item Number | |
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Bestellnummer | GTIN |
584223-25MG | 04055977264999 |
Documentation
InSolution™ Tetrahydrouridine - CAS 18771-50-1 - Calbiochem SDB
Titel |
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InSolution™ Tetrahydrouridine - CAS 18771-50-1 - Calbiochem Analysenzertifikate
Titel | Chargennummer |
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584223 |
Literatur
Übersicht |
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Yusa, K., et al. 1995. Biochem. Biophys. Res. Commun. 206, 486. Bouffard, D.Y., et al. 1993. Biochem Pharmacol. 45, 1857. Laliberte, J., et al. 1992. Cancer Chemotherap. Pharmacol. 30, 7. Riva, C., et al. 1992. Chemotherapy 38, 358. Yusa, K., et al. 1992. J. Biol. Chem. 267, 16848. Hanze, A.R. 1967. J. Am. Chem. Soc. 89, 6720. |
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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