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03-185 Histone H2B human recombinant

Human recombinant H2B expressed in E. Coli.

Histone H2B human recombinant: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Key Applications: Kinase Assay, DNA-binding Proteins, Western Blotting
03-185
50 µg  
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      Übersicht

      Replacement Information

      Key Spec Table

      Key Applications
      KA, DNA-binding Proteins, WB
      Description
      Catalogue Number03-185
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionHistone H2B human recombinant
      OverviewHuman recombinant H2B expressed in E. Coli
      Background InformationHistone H2B is one of four core histones that form an octameric structure required for the packaging of DNA into nucleosomes, the most basic level of chromatin arrangement. Histones undergo a number of post-translational modifications (PTM) at their N- and C-terminal tails which can influence chromatin structure and stability and consequently, transcription, and DNA replication and repair. The most widely studied of these modifications are methylation, phosphorylation, and acetylation which may produce different effects on gene regulation depending on the number and pattern of modifications. Histone H2B undergoes acetylation at lysines 5, 15, and 20. It is also phosphorylated in apoptotic cells during DNA fragmentation, possibly in a caspase-dependent manner.
      References
      Product Information
      FormatPurified
      PresentationLiquid in Dulbecco's PBS. Frozen solution.
      Quality LevelMQ100
      Applications
      ApplicationHuman recombinant H2B expressed in E. Coli.
      Key Applications
      • Kinase Assay
      • DNA-binding Proteins
      • Western Blotting
      Application NotesChromatin assembly, Western blot (control), Kinase Assay
      Biological Information
      HostE. coli
      PurityPurity >95% by SDS-PAGE
      Molecular Weight~17 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 12 months at -80ºC from date of receipt. Avoid multiple freeze/thaw cycles.
      Packaging Information
      Material Size50 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      03-185 04053252550799