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345701 Gambogic Acid, Garcinia hanburyi - CAS 2752-65-0 - Calbiochem

Übersicht

Key Spec Table

CAS #Empirical Formula
2752-65-0C₃₈H₄₄O₈

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345701-25MG
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      Description
      OverviewA cell-permeable caspase activator and an apoptosis inducer that was originally isolated from gamboge resin for its antimicrobial properties. Shown to inhibit the growth of HeLa and HEL cells minimal inhibitory concentrations (MIC = 12.5 µg/ml).
      Catalogue Number345701
      Brand Family Calbiochem®
      SynonymsGuttic Acid, β-Guttiferin
      References
      ReferencesPrasad, S., et al. 2011. Cancer Prev. Res. 4, 1084.
      Guo, Q.L., et al. 2004. Acta Pharmacol. Sin. 25, 769.
      Asano, J., et al. 1996. Phytochemistry 41, 815.
      Product Information
      CAS number2752-65-0
      ATP CompetitiveN
      FormAmorphous orange solid
      Hill FormulaC₃₈H₄₄O₈
      Chemical formulaC₃₈H₄₄O₈
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary TargetCaspase activator and an apoptosis inducer
      Primary Target IC<sub>50</sub>MIC = 12.5 µg/ml in inhibiting the growth of HeLa and HEL cells
      Purity≥95% by TLC
      Physicochemical Information
      Cell permeableY
      Safety Information according to GHS
      RTECSPB9268200
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Toxic & Carcinogenic / Teratogenic
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Bestellnummer GTIN
      345701-25MG 04055977193787