371818 Sigma-AldrichG-Protein βγ Binding Peptide, mSIRK - Calbiochem
A cell-permeable, N-myristoylated G-protein βγ selective binding peptide that disrupts the interaction between α and βγ subunits and promotes the α subunit dissociation without stimulating nucleotide exchange.
More>> A cell-permeable, N-myristoylated G-protein βγ selective binding peptide that disrupts the interaction between α and βγ subunits and promotes the α subunit dissociation without stimulating nucleotide exchange. Less<<SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Synonyme: mSIRK, myr-SIRKALNILGYPDYD-OH
Empfohlene Produkte
Übersicht
| Replacement Information |
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Key Spec Table
| Empirical Formula |
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| C₉₃H₁₅₀N₂₀O₂₅ |
Preis & Verfügbarkeit
| Bestellnummer | Verfügbarkeit | Verpackung | St./Pkg. | Preis | Menge | |
|---|---|---|---|---|---|---|
| 371818-1MG |
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Glasflasche | 1 mg |
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| 371818-5MG |
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Glasflasche | 5 mg |
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| Description | |
|---|---|
| Overview | A cell-permeable, N-myristoylated G-protein βγ selective binding peptide that disrupts the interaction between α and βγ subunits and promotes the α subunit dissociation without stimulating nucleotide exchange. Shown to cause a rapid activation of ERK1/2 (EC50 ~ 2.5 - 5 µM) in rat arterial smooth muscle and Rat2 cells. Also promotes the phosphorylation of JNK and p38 MAP kinase, phospholipase C and causes Ca2+ release from internal stores. Negative control is also available (Cat. No. 371820). |
| Catalogue Number | 371818 |
| Brand Family | Calbiochem® |
| Synonyms | mSIRK, myr-SIRKALNILGYPDYD-OH |
| References | |
|---|---|
| References | Goubaeva, F., et al. 2003. J. Biol. Chem. 278, 19634. Scott, J.K., et al. 2001. EMBO J. 20, 767. |
| Product Information | |
|---|---|
| ATP Competitive | N |
| Form | Lyophilized |
| Formulation | Supplied as a trifluoroacetate salt. |
| Hill Formula | C₉₃H₁₅₀N₂₀O₂₅ |
| Chemical formula | C₉₃H₁₅₀N₂₀O₂₅ |
| Hygroscopic | Hygroscopic |
| Reversible | N |
| Quality Level | MQ100 |
| Applications |
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| Physicochemical Information | |
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| Cell permeable | Y |
| Peptide Sequence | Myr-N-Ser-Ile-Arg-Lys-Ala-Leu-Asn-Ile-Leu-Gly-Tyr-Pro-Asp-Tyr-Asp-OH |
| Dimensions |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Safety Information |
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| Product Usage Statements |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
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| Supplemental Information |
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| Specifications |
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| Global Trade Item Number | |
|---|---|
| Bestellnummer | GTIN |
| 371818-1MG | 04055977213423 |
| 371818-5MG | 04055977213430 |
Documentation
G-Protein βγ Binding Peptide, mSIRK - Calbiochem SDB
| Titel |
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G-Protein βγ Binding Peptide, mSIRK - Calbiochem Analysenzertifikate
| Titel | Chargennummer |
|---|---|
| 371818 |
Literatur
| Übersicht |
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| Goubaeva, F., et al. 2003. J. Biol. Chem. 278, 19634. Scott, J.K., et al. 2001. EMBO J. 20, 767. |