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230950 Ciglitazone - CAS 74772-77-3 - Calbiochem

A potent thiazolinedione (TDZ) type anti-hyperglycemic agent and a selective PPARγ agonist (EC₅₀ = 3 µM).

Ciglitazone - CAS 74772-77-3 - Calbiochem: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.

Synonyme: (±)-5-[4-(1-Methylcyclohexylmethoxy)benzyl]thiazolidine-2,4-dione, PPAR Agonist II, PPARγ Agonist I

Primary Target: Selective PPARγ agonist
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230950
Preis & Verfügbarkeit

Übersicht

Replacement Information

Key Spec Table

CAS #Empirical Formula
74772-77-3C₁₈H₂₃NO₃S

Preis & Verfügbarkeit

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230950-5MG
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      Description
      OverviewA potent thiazolinedione (TDZ) type anti-hyperglycemic agent and a selective PPARγ agonist (EC50 = 3 µM).
      Catalogue Number230950
      Brand Family Calbiochem®
      Synonyms(±)-5-[4-(1-Methylcyclohexylmethoxy)benzyl]thiazolidine-2,4-dione, PPAR Agonist II, PPARγ Agonist I
      References
      ReferencesJha, R.J. 1999. Clin. Exp. Hypertens. 21, 157.
      Xin, X., et al. 1999. J. Biol. Chem. 274, 9116.
      Lohrke, B., et al. 1998. J. Endocrinol. 159, 429.
      Willson, T.M., et al. 1996. J. Med. Chem. 39, 665.
      Cantello, B.C., et al. 1994. J. Med. Chem. 37, 3977.
      Product Information
      CAS number74772-77-3
      ATP CompetitiveN
      FormWhite to tan solid
      Hill FormulaC₁₈H₂₃NO₃S
      Chemical formulaC₁₈H₂₃NO₃S
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetSelective PPARγ agonist
      Primary Target IC<sub>50</sub>EC50 = 3 µM as PPARγ agonist
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSXJ5813700
      Safety Information
      R PhraseR: 20/21/22

      Harmful by inhalation, in contact with skin and if swallowed.
      S PhraseS: 36

      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsStock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      230950-5MG 04055977218312

      Documentation

      Ciglitazone - CAS 74772-77-3 - Calbiochem SDB

      Titel

      Sicherheitsdatenblatt (SDB) 

      Ciglitazone - CAS 74772-77-3 - Calbiochem Analysenzertifikate

      TitelChargennummer
      230950

      Literatur

      Übersicht
      Jha, R.J. 1999. Clin. Exp. Hypertens. 21, 157.
      Xin, X., et al. 1999. J. Biol. Chem. 274, 9116.
      Lohrke, B., et al. 1998. J. Endocrinol. 159, 429.
      Willson, T.M., et al. 1996. J. Med. Chem. 39, 665.
      Cantello, B.C., et al. 1994. J. Med. Chem. 37, 3977.
      Datenblatt

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision27-January-2020 JSW
      Synonyms(±)-5-[4-(1-Methylcyclohexylmethoxy)benzyl]thiazolidine-2,4-dione, PPAR Agonist II, PPARγ Agonist I
      DescriptionA potent thiazolinedione (TDZ) type anti-hyperglycemic agent and a selective peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC50 = 3 µM).
      FormWhite to tan solid
      CAS number74772-77-3
      RTECSXJ5813700
      Chemical formulaC₁₈H₂₃NO₃S
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (≥ 25 mg/ml) or Ethanol (≥25 mg/ml)
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsStock solutions are stable for up to 3 months at -20°C.
      Toxicity Harmful
      ReferencesJha, R.J. 1999. Clin. Exp. Hypertens. 21, 157.
      Xin, X., et al. 1999. J. Biol. Chem. 274, 9116.
      Lohrke, B., et al. 1998. J. Endocrinol. 159, 429.
      Willson, T.M., et al. 1996. J. Med. Chem. 39, 665.
      Cantello, B.C., et al. 1994. J. Med. Chem. 37, 3977.