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MABF1961 Anti-Thy 1.1 (CD90) Antibody, clone T11D7e

This mouse monoclonal Anti-Thy 1.1 (CD90), clone T11D7e, Cat. No. MABF1961 is validated for use in Flow Cytometry for the detection of Thy-1 membrane glycoprotein, CD90.

Anti-Thy 1.1 (CD90) Antibody, clone T11D7e: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Research Category: Inflammation & Immunology Gene Symbol: Thy1, Thy-1 UniProt Number: P01830
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MABF1961
200 µL  
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      Übersicht

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      R, MFCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABF1961
      DescriptionAnti-Thy 1.1 (CD90) Antibody, clone T11D7e
      Alternate Names
      • Thy-1 membrane glycoprotein
      • Thy-1 antigen
      • CD90
      Background InformationThy-1 membrane glycoprotein (UniProt: P01830; also known as Thy-1 antigen, CD90) is encoded by the Thy1 (also known as Thy-1) gene (Gene ID: 24832) in rat. Thy-1 is a heavily glycosylated, GPI-anchored membrane glycoprotein that is distributed throughout mammalian species. Thy-1 is synthesized with a 19 amino acid signal sequence and 31 amino acid C-terminal transmembrane domain that is present in pro form, but removed when transferring the 112 amino acid mature peptide to GPI anchor. It is present in large amounts on thymus and brain cells and in smaller quantities on fibroblasts, epidermal cells, mammary glands and immature skeletal muscle. In many of these tissues the level of Thy-1 expression changes dramatically during cell differentiation. Thy-1 plays a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. Thy-1 is one of the most heavily glycosylated membrane proteins with a carbohydrate content up to 30% of its molecular mass. In most species Thy-1 has 3 N-glycosylation sites (Asn 23, 74, and 98) but no O-glycosylation. The glycosylation appears to be tissue specific and the composition of Thy-1 carbohydrate moieties is shown to vary between different tissues or even among cells of the same lineage at different stages of differentiation. Thy-1 is a differentiation marker for thymocytes and can serve as a surrogate marker for various kinds of stem cells.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal antibody IgM in PBS with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis mouse monoclonal Anti-Thy 1.1 (CD90), clone T11D7e, Cat. No. MABF1961 is validated for use in Flow Cytometry for the detection of Thy-1 membrane glycoprotein, CD90.
      Key Applications
      • Flow Cytometry
      Application NotesFlow Cytometry Analysis: A representative lot detected Thy 1.1 (CD90) in CAK1.3 and CAK4.4 cell lines (Ogasawara, K., et. al. (1990). Microbiol. Immunol. 34(12):1025-39).
      Biological Information
      ImmunogenXenogenic rat thymocytes.
      Epitopeextracellular domain
      CloneT11D7e
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      SpecificityClone T11D7e detects Thy-1.1 (CD90) in rat thymocytes.
      IsotypeIgMκ
      Species Reactivity
      • Rat
      • Mouse
      Species Reactivity NoteRat, Mouse.
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • Thy1
      • Thy-1
      UniProt Number
      Molecular Weight18.17 kDa calulated
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Flow Cytometry in rat thymocytes.

      Flow Cytometry Analysis: 1 µg of this antibody detected Thy 1.1 (CD90) in one million rat thymocytes.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size200 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      MABF1961 04054839168703