Millipore Sigma Vibrant Logo

437695 Anti-Lipoic Acid Rabbit pAb

This Anti-Lipoic Acid Rabbit pAb is validated for use in ELISA, Frozen Sections, Immunoblotting, Paraffin Sections for the detection of Lipoic Acid.

Anti-Lipoic Acid Rabbit pAb: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.

Synonyme: Anti-LA

View Products on Sigmaaldrich.com
437695
Preis & Verfügbarkeit

Übersicht

Replacement Information

Key Spec Table

Species ReactivityHostAntibody Type
A Broad Range Of SpeciesRbPolyclonal Antibody

Preis & Verfügbarkeit

Bestellnummer VerfügbarkeitVerpackung St./Pkg. Preis Menge
437695-100UL
Verfügbarkeit wird abgerufen...
—
Eingeschränkte Verfügbarkeit Eingeschränkte Verfügbarkeit
Lieferbar 
Produkt wurde eingestellt
Begrenzter Lagerbestand
Bestätigung der Verfügbarkeit erforderlich
    Restmenge: Angebot folgt
      Restmenge: Angebot folgt
      Bitte erfragen
      Kontakt zum Kundenservice
      Contact Customer Service

      		 Kst.-Ampulle 100 ul
      Preis wird abgerufen...
      Preis nicht abrufbar
      Die Mindestmenge muss ein Vielfaches sein von
      Maximum Quantity is
      Bei Bestätigung Weitere Informationen
      Sie haben () gespart
       
      —
      Bitte erfragen
      		 —
      Description
      OverviewRecognizes native lipoic acid. Does not recognize lipoic acid modified by 4-HNE (4-hydroxy-2-noneal) and other lipid peroxidation products.
      Catalogue Number437695
      Brand Family Calbiochem®
      SynonymsAnti-LA
      References
      ReferencesSasaki, M., et al. 2000. J. Autoimmun. 15, 51.
      Heitzer, T., et al. 2001. Free Radic. Biol. Med. 31, 53.
      Patrick. L. 2000. Altern. Med. Rev. 5, 290.
      Shi, S.S., et al. 1999. Antioxid. Redox Signal 1, 123.
      Humphries, K.M. and Szeda, L.I. 1998. Biochemistry 37, 15835.
      Product Information
      FormLiquid
      Formulationserum diluted in buffer, 50% glycerol, pH 7.5.
      PreservativeNone
      Quality LevelMQ100
      Applications
      Key Applications Enzyme-Linked Immunosorbent Assay
      Frozen Sections
      Immunoblotting (Western Blotting)
      Paraffin Sections
      Application NotesELISA (1:500-1:1000)
      Frozen Sections (1:50-1:500)
      Immunoblotting (1:1000-1:10,000)
      Paraffin Sections (1:50-1:500)
      Application CommentsDoes not bind lipoic acid modified by 4-HNE (4-hydroxy-2-noneal) and other lipid peroxidation products. Useful for assessing whether protein-bound lipoic acids have undergone certain forms of oxidative modification. The presence of protein-bound lipoic acid can be used as a marker for mitochondria. Variables associated with assay conditions will dictate the optimal working dilution.
      Biological Information
      Immunogenlipoic acid conjugated to KLH
      HostRabbit
      IsotypeIgG
      Species Reactivity
      • A Broad Range Of Species
      Antibody TypePolyclonal Antibody
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      437695-100UL 07790788059934

      Documentation

      Anti-Lipoic Acid Rabbit pAb SDB

      Titel

      Sicherheitsdatenblatt (SDB) 

      Anti-Lipoic Acid Rabbit pAb Analysenzertifikate

      TitelChargennummer
      437695

      Literatur

      Übersicht
      Sasaki, M., et al. 2000. J. Autoimmun. 15, 51.
      Heitzer, T., et al. 2001. Free Radic. Biol. Med. 31, 53.
      Patrick. L. 2000. Altern. Med. Rev. 5, 290.
      Shi, S.S., et al. 1999. Antioxid. Redox Signal 1, 123.
      Humphries, K.M. and Szeda, L.I. 1998. Biochemistry 37, 15835.
      Datenblatt

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision07-August-2007 RFH
      SynonymsAnti-LA
      ApplicationELISA (1:500-1:1000)
      Frozen Sections (1:50-1:500)
      Immunoblotting (1:1000-1:10,000)
      Paraffin Sections (1:50-1:500)
      DescriptionRabbit polyclonal antibody supplied as diluted serum. Recognizes native lipoic acid and lipoic acid covalently attached to proteins.
      BackgroundLipoic acid is a sulfur-containing substance that is readily converted to and from its reduced form, dihydrolipoic acid. It acts as a coenzyme in reactions that occur in the Krebs cycle; specifically it is involved in the decarboxylation of pyruvate and some other alpha-keto acids. Protein-bound lipoic acids such as E2 subunits, α-ketoglutarate dehydrogenase, or pyruvate dehydrogenase have been shown to be highly susceptible to free radical-derived oxidative modification. Lipoic acid is able to deactivate both fat and water soluble free radicals and thereby protect both lipoproteins and membranes; no other anti-oxidant can do this. It has also shown great promise in the treatment of HIV and in diabetes.
      HostRabbit
      Immunogenlipoic acid conjugated to KLH
      IsotypeIgG
      Speciesa broad range of species
      FormLiquid
      Formulationserum diluted in buffer, 50% glycerol, pH 7.5.
      PreservativeNone
      CommentsDoes not bind lipoic acid modified by 4-HNE (4-hydroxy-2-noneal) and other lipid peroxidation products. Useful for assessing whether protein-bound lipoic acids have undergone certain forms of oxidative modification. The presence of protein-bound lipoic acid can be used as a marker for mitochondria. Variables associated with assay conditions will dictate the optimal working dilution.
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      ReferencesSasaki, M., et al. 2000. J. Autoimmun. 15, 51.
      Heitzer, T., et al. 2001. Free Radic. Biol. Med. 31, 53.
      Patrick. L. 2000. Altern. Med. Rev. 5, 290.
      Shi, S.S., et al. 1999. Antioxid. Redox Signal 1, 123.
      Humphries, K.M. and Szeda, L.I. 1998. Biochemistry 37, 15835.