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ABT405 Anti-KIF5 Antibody

Anti-KIF5 Antibody is an antibody against KIF5 for use in western blotting, ICC & immunofluorescence.

Anti-KIF5 Antibody: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Research Category: Cell Structure Research Sub-Category: Cytoskeleton Gene Symbol: KIF5A, NKHC1 UniProt Number: Q12840
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ABT405
100 µg  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, ICC, IFRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABT405
      DescriptionAnti-KIF5 Antibody
      Alternate Names
      • Kinesin heavy chain isoform 5A
      • Kinesin heavy chain neuron-specific 1
      • Neuronal kinesin heavy chain
      • NKHC
      • KIF5A
      Background InformationKinesin heavy chain isoform 5A, also known as Kinesin heavy chain neuron-specific 1 or Neuronal kinesin heavy chain (NKHC), and encoded by the gene name KIF5A or NKHC1, are members of the kinesin superfamily of proteins (KIFs). These proteins are microtubuledependent motors that slide along microtubules and transport cellular organelles and mRNA to different parts of the cell. In neurons, KIF5 performs this role in an anterograde fashion from the neuronal cell body to axonal or dendritic terminals. KIF5 was initially differentiated from the ubiquitously expressed kinesin as being highly enriched in subsets of neurons and selectively concentrated in the cell body. KIF5 has at least three known isoforms; KIF5A (117 kDa), KIF5B (39 kDa), and KIF5C (39 kDa). Mutations in one of the isoforms of KIF5 (KIF5A) is thought to be involved in hereditary spastic paraplegias
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-KIF5 Antibody is an antibody against KIF5 for use in western blotting, ICC & immunofluorescence.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      • Immunofluorescence
      Application NotesImmunocytochemistry Analysis: 5 μg/mL from a representative lot detected KIF5 in K562 cells.

      Immunofluorescence Analysis: 20 μg/mL from a representative lot detected KIF5 in K562 cells.
      Biological Information
      ImmunogenKLH-conjugated synthetic peptide corresponding to the C-terminus of human KIF5.
      EpitopeC-terminus
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody recognizes all isoforms of KIF5.
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • KIF5A
      • NKHC1
      Purification MethodAffinity
      UniProt Number
      Molecular Weight~116 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in K562 cell lysate.

      Western Blotting Analysis: 1 μg/mL of this antibody detected KIF5 in K562 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      ABT405 04053252944017

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      Kategorien

      Life Science Research > Antibodies and Assays > Primary Antibodies