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MABS419 Anti-BMPR-1A, clone 4B7B2 Antibody

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MABS419
100 µL  
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      Übersicht

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, MWB, IHC, FC, ELISAMAscitesMonoclonal Antibody
      Description
      Catalogue NumberMABS419
      DescriptionAnti-BMPR-1A, clone 4B7B2 Antibody
      Alternate Names
      • Bone morphogenetic protein receptor type-1A
      • BMP type-1A receptor
      • BMPR-1A
      Background InformationBMPR-1A (bone morphogenic protein receptor type 1A) signaling is known to be important for inner root sheath differentiation, hair follicle cycling and tooth development. Mutations in BMPR-1A are a common cause of juvenile polyposis syndrome (JPS). BMPR-1A is expressed in a high quantity during the formation of the primary and secondary palate and the loss of BMPR-1A could be a cause for the cleft palate birth defect.
      Product Information
      FormatAscites
      PresentationMouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-BMPR-1A, clone 4B7B2 Antibody is validated for use in western blotting, IHC, flow cytometry & ELISA for the detection of BMPR-1A.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      • Flow Cytometry
      • ELISA
      Application NotesImmunohistochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected BMPR-1A in colon cancer and kidney tissues.

      Flow Cytometry Analysis: A 1;200-400 dilution from a representative lot detected BMPR-1A in HeLa cells.

      ELISA: A representative lot detected control Antigen (100 ng) and Antigen (10 ng, 50 ng, 100 ng) in ELISA (Direct).
      Biological Information
      ImmunogenPurified recombinant fragment of human BMPR1A expressed in E. Coli
      Clone4B7B2
      HostMouse
      IsotypeIgG1
      Species Reactivity
      • Human
      • Mouse
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • BMPR1A
      • ACVRLK3
      • ALK3
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~65 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in PC-3, K562 and mouse liver lysates.

      Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected BMPR-1A in PC-3, K562 and mouse liver lysates.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Global Trade Item Number
      Bestellnummer GTIN
      MABS419 04053252957826