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07-262 Anti-Arg Antibody, SH3/SH2

Anti-Arg Antibody, SH3/SH2 is an antibody against Arg for use in IH, IP & WB.

Anti-Arg Antibody, SH3/SH2: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Research Category: Signaling Research Sub-Category: Insulin/Energy Signaling Gene Symbol: ABL2, Abelson-related, ABLL, ARG UniProt Number: P42684
07-262
200 µL  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MIHC, IP, WBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue Number07-262
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-Arg Antibody, SH3/SH2
      References
      Product Information
      FormatAffinity Purified
      Presentation0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
      Applications
      ApplicationAnti-Arg Antibody, SH3/SH2 is an antibody against Arg for use in IH, IP & WB.
      Key Applications
      • Immunohistochemistry
      • Immunoprecipitation
      • Western Blotting
      Biological Information
      ImmunogenGST fusion protein corresponding to the SH2 and SH3 domains of murine Arg (Abl-related gene), residues 112-259
      HostRabbit
      SpecificityArg
      IsotypeIgG
      Species Reactivity
      • Mouse
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThe gene product is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. This gene is expressed in both normal and tumor cells. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
      Gene Symbol
      • ABL2
      • Abelson-related
      • ABLL
      • ARG
      Purification MethodImmunoaffinity Chromatography
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P42684 # Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics.
      COFACTOR: Magnesium or manganese.
      SIZE: 1182 amino acids; 128343 Da
      SUBCELLULAR LOCATION: Cytoplasm.
      TISSUE SPECIFICITY: Widely expressed.
      PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.
      SIMILARITY: SwissProt: P42684 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. ABL subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.
      Molecular Weight135 & 140kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by immunoblot on RIPA lysates from Mouse Brain Cytosol
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions1 year at -20°C
      Packaging Information
      Material Size200 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      07-262 04053252625114