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129875 Amastatin, Streptomyces sp. - CAS 67655-94-1 - Calbiochem

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Synonyme: (2S,3R)-3-Amino-2-hydroxy-5-methylhexanoyl-Val-Val-Asp-OH

Primary Target: Aminopeptidase A
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      Übersicht

      Replacement Information

      Key Spec Table

      CAS #
      67655-94-1
      Description
      Overview

      This product has been discontinued.



      Non-toxic inhibitor of aminopeptidase A (Ki = 1 µM) and leucine aminopeptidase. Also acts as a slow-binding, competitive inhibitor of aminopeptidase M. Does not inhibit aminopeptidase B, chymotrypsin, elastase, papain, pepsin, thermolysin, or trypsin.
      Catalogue Number129875
      Brand Family Calbiochem®
      Synonyms(2S,3R)-3-Amino-2-hydroxy-5-methylhexanoyl-Val-Val-Asp-OH
      References
      ReferencesRich, D.H., et al. 1984. J. Med. Chem. 27, 417.
      Jobe, H., et al. 1979. Agric. Biol. Chem. 43, 591.
      Aoyagi, T., et al. 1978. J. Antibiot. 31, 636.
      Product Information
      CAS number67655-94-1
      ATP CompetitiveN
      FormColorless amorphous solid
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetAminopeptidase A
      Primary Target K<sub>i</sub>1 µM against aminopeptidase A
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSCI9098850
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +15°C to +30°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      129875 0

      Documentation

      Amastatin, Streptomyces sp. - CAS 67655-94-1 - Calbiochem Analysenzertifikate

      TitelChargennummer
      129875

      Literatur

      Übersicht
      Rich, D.H., et al. 1984. J. Med. Chem. 27, 417.
      Jobe, H., et al. 1979. Agric. Biol. Chem. 43, 591.
      Aoyagi, T., et al. 1978. J. Antibiot. 31, 636.
      Datenblatt

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision03-October-2007 RFH
      Synonyms(2S,3R)-3-Amino-2-hydroxy-5-methylhexanoyl-Val-Val-Asp-OH
      DescriptionNon-toxic specific inhibitor of aminopeptidase A and leucine aminopeptidase. Also acts as a slow-binding, competitive inhibitor of aminopeptidase M. Does not inhibit aminopeptidase B, chymotrypsin, elastase, papain, pepsin, thermolysin, or trypsin.
      FormColorless amorphous solid
      CAS number67655-94-1
      RTECSCI9098850
      Structure formulaStructure formula
      Purity≥97% by HPLC
      SolubilityDMSO (10 mg/ml)
      Storage +15°C to +30°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Toxicity Standard Handling
      ReferencesRich, D.H., et al. 1984. J. Med. Chem. 27, 417.
      Jobe, H., et al. 1979. Agric. Biol. Chem. 43, 591.
      Aoyagi, T., et al. 1978. J. Antibiot. 31, 636.