Millipore Sigma Vibrant Logo

100122 A3, Hydrochloride

A3, Hydrochloride: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.

Synonyme: N-(2-Aminoethyl)-5-chloronaphthalene-1-sulfonamide, HCl

Primary Target: CK1
100122
  
Preis wird abgerufen...
Preis nicht abrufbar
Die Mindestmenge muss ein Vielfaches sein von
Maximum Quantity is
Bei Bestätigung Weitere Informationen
Sie haben () gespart
 
—
Bitte erfragen
—
Eingeschränkte Verfügbarkeit Eingeschränkte Verfügbarkeit
Lieferbar 
Produkt wurde eingestellt
Begrenzter Lagerbestand
Bestätigung der Verfügbarkeit erforderlich
    Restmenge: Angebot folgt
      Restmenge: Angebot folgt
      Bitte erfragen
      Kontakt zum Kundenservice
      Contact Customer Service

       

      Kontakt zum Kundenservice

      Übersicht

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      78957-85-4C₁₂H₁₃ClN₂O₂S · HCl
      Description
      Overview

      This product has been discontinued.





      A cell-permeable, reversible, and shorter alkyl chain derivative of W-7 that inhibits casein kinase I (Ki = 80 µM), casein kinase II (Ki = 5.1 µM), myosin light chain kinase (Ki = 7.4 µM), protein kinase A (Ki = 4.3 µM), protein kinase C (Ki = 47 µM), and protein kinase G (Ki = 3.8 µM).
      Catalogue Number100122
      Brand Family Calbiochem®
      SynonymsN-(2-Aminoethyl)-5-chloronaphthalene-1-sulfonamide, HCl
      References
      ReferencesInagaki, M., et al. 1986. Mol. Pharmacol. 29, 577.
      Turner, E.J.H., et al. 2003. Br. J. Haematol. 120, 894.
      Product Information
      CAS number78957-85-4
      FormOff-white solid
      Hill FormulaC₁₂H₁₃ClN₂O₂S · HCl
      Chemical formulaC₁₂H₁₃ClN₂O₂S · HCl
      Hygroscopic Hygroscopic
      Structure formula ImageStructure formula Image
      Applications
      Biological Information
      Primary TargetCK1
      Primary Target K<sub>i</sub>80 µM
      Secondary targetCK2 (Ki = 5.1 µM), MLCK (Ki = 7.4 µM), PKA (Ki = 4.3 µM), PKC (Ki = 47 µM), PKG (Ki = 3.8 µM)
      Purity≥98% by TLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). DMSO stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      100122 0

      Documentation

      A3, Hydrochloride Analysenzertifikate

      TitelChargennummer
      100122

      Literatur

      Übersicht
      Inagaki, M., et al. 1986. Mol. Pharmacol. 29, 577.
      Turner, E.J.H., et al. 2003. Br. J. Haematol. 120, 894.
      Datenblatt

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision04-April-2011 RFH
      SynonymsN-(2-Aminoethyl)-5-chloronaphthalene-1-sulfonamide, HCl
      DescriptionA cell-permeable, reversible, and shorter alkyl chain derivative of W-7 that inhibits casein kinase I (Ki= 80 µM), casein kinase II (Ki= 5.1 µM), myosin light chain kinase (Ki= 7.4 µM), protein kinase A (Ki= 4.3 µM), protein kinase C (Ki= 47 µM) and protein kinase G (Ki= 3.8 µM).
      FormOff-white solid
      CAS number78957-85-4
      Chemical formulaC₁₂H₁₃ClN₂O₂S · HCl
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityDMSO (25 mg/ml) or 50% Ethanol (20 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). DMSO stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesInagaki, M., et al. 1986. Mol. Pharmacol. 29, 577.
      Turner, E.J.H., et al. 2003. Br. J. Haematol. 120, 894.

      Verwandte Produkte & Anwendungen

      Kategorien

      Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Protein Phosphorylation / Dephosphorylation > Casein Kinase (CK) Inhibitors
      Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Protein Phosphorylation / Dephosphorylation > Myosin Light Chain Kinase (MLCK) Inhibitors
      Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Protein Phosphorylation / Dephosphorylation > Protein Kinase A (PKA; cAMP-Dependent Protein Kinase) Inhibitors
      Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Protein Phosphorylation / Dephosphorylation > Protein Kinase G (PKG; cGMP-Dependent Protein Kinase) Inhibitors