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504344 (+)-WIN 55,212-2 mesylate - CAS 131543-23-2 - Calbiochem

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Synonyme: WIN 55,212-2 MESYLATE, WIN55, R(+)-WIN 55,212-2 ,MESYLATE HIGH AFFINIT Y CANNABI, R(+)-WIN 55,212-2 MESYLATE, WIN 55,212-2, (R)-(+)-(2,3; Dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1.2.3-de]-1,4-benzoxazin-6-yl)-1-naphthalenylmethanonemesy;, 212-2Mesylate

Primary Target: CB receptors
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      Übersicht

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      131543-23-2C₂₇H₂₆N₂O₃ CH₃SO₃H
      Description
      OverviewA potent agonist for cannabinoid receptors with higher affinity to subtype 2 (CB2, Ki = 3.3 nM) than to subtype 1 (CB1, Ki = 62.3 nM).
      Catalogue Number504344
      Brand Family Calbiochem®
      SynonymsWIN 55,212-2 MESYLATE, WIN55, R(+)-WIN 55,212-2 ,MESYLATE HIGH AFFINIT Y CANNABI, R(+)-WIN 55,212-2 MESYLATE, WIN 55,212-2, (R)-(+)-(2,3; Dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1.2.3-de]-1,4-benzoxazin-6-yl)-1-naphthalenylmethanonemesy;, 212-2Mesylate
      References
      ReferencesPalazzo, E., et al. 2012. Neuroscience. 85, 327.
      Ferraro, L., et al. 2001. Cerebral Cortex. 11,728.
      Price, T., et al. 2004. Br. J. Pharmacol. 142, 257.
      Martellotta, M., et al. 1998. Neuroscience. 85, 327.
      Griffin,G., et al. 1998. J. Pharmacol. Exp. Ther. 285, 553.
      Product Information
      CAS number131543-23-2
      FormOff-white solid
      Hill FormulaC₂₇H₂₆N₂O₃ CH₃SO₃H
      Chemical formulaC₂₇H₂₆N₂O₃ CH₃SO₃H
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetCB receptors
      Primary Target K<sub>i</sub>62.3 and 3.3 nM for CB₁ and CB₂ receptors, respecively.
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -30°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      504344 0

      Documentation

      (+)-WIN 55,212-2 mesylate - CAS 131543-23-2 - Calbiochem SDB

      Titel

      Sicherheitsdatenblatt (SDB) 

      Literatur

      Übersicht
      Palazzo, E., et al. 2012. Neuroscience. 85, 327.
      Ferraro, L., et al. 2001. Cerebral Cortex. 11,728.
      Price, T., et al. 2004. Br. J. Pharmacol. 142, 257.
      Martellotta, M., et al. 1998. Neuroscience. 85, 327.
      Griffin,G., et al. 1998. J. Pharmacol. Exp. Ther. 285, 553.
      Datenblatt

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision21-June-2013 JSW
      SynonymsWIN 55,212-2 MESYLATE, WIN55, R(+)-WIN 55,212-2 ,MESYLATE HIGH AFFINIT Y CANNABI, R(+)-WIN 55,212-2 MESYLATE, WIN 55,212-2, (R)-(+)-(2,3; Dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1.2.3-de]-1,4-benzoxazin-6-yl)-1-naphthalenylmethanonemesy;, 212-2Mesylate
      DescriptionA potent agonist for cannabinoid receptors with higher affinity to subtype 2 (CB2, Ki = 3.3 nM) than to subtype 1 (CB1, Ki = 62.3 nM).
      FormOff-white solid
      CAS number131543-23-2
      Chemical formulaC₂₇H₂₆N₂O₃ CH₃SO₃H
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (30 mg/ml)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -30°C.
      Toxicity Standard Handling
      ReferencesPalazzo, E., et al. 2012. Neuroscience. 85, 327.
      Ferraro, L., et al. 2001. Cerebral Cortex. 11,728.
      Price, T., et al. 2004. Br. J. Pharmacol. 142, 257.
      Martellotta, M., et al. 1998. Neuroscience. 85, 327.
      Griffin,G., et al. 1998. J. Pharmacol. Exp. Ther. 285, 553.