Millipore Sigma Vibrant Logo

428025 α-Latrotoxin, Latrodectus tredecimguttatus - CAS 65988-34-3 - Calbiochem

Causes massive release of exocytotic neurotransmitter synaptic vesicles from a wide variety of central and peripheral synaptic junctions of vertebrates via Ca2+-dependent and -independent parallel mechanisms at concentrations as low as 100 pM.

SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.

Synonyme: α-Ltx

428025
  
Preis wird abgerufen...
Preis nicht abrufbar
Die Mindestmenge muss ein Vielfaches sein von
Maximum Quantity is
Bei Bestätigung Weitere Informationen
Sie haben () gespart
 
—
Bitte erfragen
—
Eingeschränkte Verfügbarkeit Eingeschränkte Verfügbarkeit
Lieferbar 
Produkt wurde eingestellt
Begrenzter Lagerbestand
Bestätigung der Verfügbarkeit erforderlich
    Restmenge: Angebot folgt
      Restmenge: Angebot folgt
      Bitte erfragen
      Kontakt zum Kundenservice
      Contact Customer Service

       

      Kontakt zum Kundenservice

      Übersicht

      Replacement Information

      Key Spec Table

      CAS #
      65988-34-3
      Description
      OverviewCauses massive release of exocytotic neurotransmitter synaptic vesicles from a wide variety of central and peripheral synaptic junctions of vertebrates via Ca2+-dependent and -independent parallel mechanisms at concentrations as low as 100 pM. Stimulates Ca2+-independent GABA and glutamate release from cortical astrocytes in culture.
      Catalogue Number428025
      Brand Family Calbiochem®
      Synonymsα-Ltx
      References
      ReferencesParpura, V., et al. 1995. FEBS Lett. 360, 266.
      Storchak, L.G., et al. 1994. FEBS Lett. 351, 267.
      Osipenko, O.N., et al. 1993. Toxicon 31, 1123.
      Valtorta, F., et al. 1988. J. Cell Biol. 107, 2717.
      Grasso, A. 1976. Biochem. Biophys. Acta 439, 406.
      Frontali, B., et al. 1976. J. Cell Biol. 68, 462.
      Product Information
      CAS number65988-34-3
      ATP CompetitiveN
      FormWhite lyophilized solid
      ReversibleN
      Applications
      Biological Information
      Biological activityEffective concentration: 100 pm-1 nm
      Primary TargetCauses release of exocytotic neurotransmitter synaptic vesicles from a wide variety of central and peripheral synaptic junctions of vertebrates
      PurityOne distinct band by SDS-PAGE
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSOE9020000
      Safety Information
      R PhraseR: 20/21/22

      Harmful by inhalation, in contact with skin and if swallowed.
      S PhraseS: 36

      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 year at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      428025 0

      Documentation

      α-Latrotoxin, Latrodectus tredecimguttatus - CAS 65988-34-3 - Calbiochem SDB

      Titel

      Sicherheitsdatenblatt (SDB) 

      α-Latrotoxin, Latrodectus tredecimguttatus - CAS 65988-34-3 - Calbiochem Analysenzertifikate

      TitelChargennummer
      428025

      Literatur

      Übersicht
      Parpura, V., et al. 1995. FEBS Lett. 360, 266.
      Storchak, L.G., et al. 1994. FEBS Lett. 351, 267.
      Osipenko, O.N., et al. 1993. Toxicon 31, 1123.
      Valtorta, F., et al. 1988. J. Cell Biol. 107, 2717.
      Grasso, A. 1976. Biochem. Biophys. Acta 439, 406.
      Frontali, B., et al. 1976. J. Cell Biol. 68, 462.
      Datenblatt

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision07-April-2008 RFH
      Synonymsα-Ltx
      DescriptionCauses massive release of exocytotic neurotransmitter synaptic vesicles from a wide variety of central and peripheral synaptic junctions of vertebrates via Ca2+-dependent and independent parallel mechanisms at concentrations as low as 100 pM. Stimulates Ca2+-independent GABA and glutamate release from cortical astrocytes in culture.
      FormWhite lyophilized solid
      CAS number65988-34-3
      RTECSOE9020000
      PurityOne distinct band by SDS-PAGE
      Biological activityEffective concentration: 100 pm-1 nm
      SolubilityDissolve in 0.5 ml cold H₂O with gentle stirring; add 0.5 ml glycerol yeilding a stock solution of 300 nm α-latrotoxin in 50% glycerol.
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 year at -20°C.
      Toxicity Harmful
      ReferencesParpura, V., et al. 1995. FEBS Lett. 360, 266.
      Storchak, L.G., et al. 1994. FEBS Lett. 351, 267.
      Osipenko, O.N., et al. 1993. Toxicon 31, 1123.
      Valtorta, F., et al. 1988. J. Cell Biol. 107, 2717.
      Grasso, A. 1976. Biochem. Biophys. Acta 439, 406.
      Frontali, B., et al. 1976. J. Cell Biol. 68, 462.