MABF384
Anti-CD127 (IL-7Ra) Antibody (mouse), clone A7R34
clone A7R34, 0.5 mg/mL, from rat
동의어(들):
Interleukin-17 receptor A, IL-17 receptor A, IL-17RA, CD217
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
제품 이름
Anti-CD127 (IL-7Ra) Antibody (mouse), clone A7R34, clone A7R34, 0.5 mg/mL, from rat
biological source
rat
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
A7R34, monoclonal
species reactivity
mouse
concentration
0.5 mg/mL
technique(s)
flow cytometry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
isotype
IgG2aκ
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
mouse ... Il7R(16197)
Application
This Rat Monoclonal Antibody Anti-CD127 (IL-7Ra) (mouse), clone A7R34, Cat. No. MABF384 is validated for use in IP, IHC, Immunofluorescence and Flow Cytometry for the detection of CD127 (IL-7Ra).
General description
The A7R34 antibody is specific for mouse CD127, a 60-90 kDa cell surface protein also known as the Interleukin-7 Receptor alpha chain, or IL-7R alpha. CD127 is typically expressed at the cell surface as a heterodimer with the common gamma chain (CD132). This complex acts as the functional receptor for IL-7, a cytokine important in T and B cell development, and in mature T cell homeostasis. A second cytokine known as Thymic Stromal Lymphopoietin (TSLP) also binds to a receptor complex of CD127 and the TSLPR chain to trigger activation of dendritic cells, and is involved in B cell development, allergy and autoimmunity.The A7R34 antibody may be used as a phenotypic marker for CD127 on immature B cells, on subsets of thymocytes which are double negative (CD4-CD8- ) or single positive (CD4+ or CD8+), and at low levels on mature, peripheral T cells. CD127 is a key marker, when used in combination with CD4 and CD25, to distinguish Treg and effector/memory Treg populations known as T(REM).
Physical form
Format: Purified
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저장 등급
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Gabrielle L Goldberg et al.
Journal of immunology (Baltimore, Md. : 1950), 184(11), 6014-6024 (2010-05-21)
Cytotoxic antineoplastic therapy is used to treat malignant disease but results in long-term immunosuppression in postpubertal and adult individuals, leading to increased incidence and severity of opportunistic infections. We have previously shown that sex steroid ablation (SSA) reverses immunodeficiencies associated
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| MABF384 | 04053252959608 |
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