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Merck

MAB3786

Anti-APC Antibody, CT, clone C-APC 28.9

clone C-APC 28.9, Chemicon®, from mouse

동의어(들):

Adenomatous Polyposis Coli Protein

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
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제품 이름

Anti-APC Antibody, CT, clone C-APC 28.9, clone C-APC 28.9, Chemicon®, from mouse

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

C-APC 28.9, monoclonal

species reactivity

human, mouse

packaging

antibody small pack of 25 μg

manufacturer/tradename

Chemicon®

technique(s)

immunofluorescence: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG1κ

NCBI accession no.

UniProt accession no.

shipped in

ambient

storage temp.

2-8°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... APC(324)
mouse ... Apc(11789)

Analysis Note

Control
POSITIVE CONTROL: colon cell line HCT116
Tested

Application

Anti-APC Antibody, C-terminus, clone C-APC 28.9 is a Mouse Monoclonal Antibody for detection of APC also known as Adenomatous Polyposis Coli Protein & has been validated in IF, IP, WB & IHC.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Cell Cycle, DNA Replication & Repair
Western blot

Immunohistochemistry (Frozen sections)

Immunofluorescence

Immunoprecipitation

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Recognizes human APC, molecular weight is approximately 310kDa.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

The adenomatous polyposis coli tumor suppressor gene is mutated (often deletion of the C-terminal portion of APC) in the inherited disease, familial adenomatous polyposis (FAP), and over 80% of colorectal cancers. C-APC 28.8 can be used for APC expression and detection of APC mutations.

Immunogen

Epitope: C-terminus
Human APC C-terminal fusion with MBP (maltose binding protein).

Other Notes

Please refer to lot specific datasheet.

Physical form

Format: Purified
Purified immunoglobulin. Liquid in 0.02M phosphate buffer, 0.25M NaCl, pH 7.6, with 0.1% sodium azide.

Preparation Note

Maintain at 2-8°C in undiluted aliquots for up to 12 months from date of receipt.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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저장 등급

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Mirjana Kessler et al.
The American journal of pathology, 180(1), 186-198 (2011-11-10)
The obligate intracellular pathogen Chlamydia trachomatis (Ctr) is a major cause of sexually transmitted disease and infertility worldwide. Ascending genital infections cause inflammation of fallopian tubes and subsequent scarring and occlusion. The cellular basis for such sequelae remains undetermined. We
Jing Zhou et al.
Journal of cellular and molecular medicine, 18(2), 326-343 (2014-01-01)
Stem cell transplantation represents a promising strategy for the repair of spinal cord injury (SCI). However, the low survival rate of the grafted cells is a major obstacle hindering clinical success because of ongoing secondary injury processes, which includes excitotoxicity

국제 무역 품목 번호

SKUGTIN
MAB378604053252723834
MAB3786-25UG04054839350399

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