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Merck

AP506P

Goat Anti-Human Ig λ chain Antibody, HRP conjugate

Chemicon®, from goat

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
peroxidase conjugate
Clone:
polyclonal
Application:
ELISA
Species reactivity:
human
Citations:
2
Technique(s):
ELISA: suitable
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제품 이름

Goat Anti-Human Ig λ chain Antibody, HRP conjugate, Chemicon®, from goat

Quality Level

biological source

goat

conjugate

peroxidase conjugate

antibody form

affinity purified immunoglobulin

antibody product type

secondary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable

shipped in

wet ice

target post-translational modification

unmodified

Application

ELISA: 1:4,000-1:8,000.

Optimal working dilutions must be determined by the end user.
Goat anti-Human Ig λ chain Antibody, HRP conjugate detects level of Human Ig λ chain & has been published & validated for use in ELISA.
Research Category
Secondary & Control Antibodies
Research Sub Category
Fragment Specific Secondary Antibodies

Biochem/physiol Actions

Reacts with human lambda light chains. Absorbed for human myeloma proteins with kappa light chains.
The antibody reacts with human lambda light chains as demonstrated by ELISA and flow cytometry.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Antibody molecules typically comprise two immunoglobulin light chains covalently bound to a pair of heavy chains. Immunoglobulin light chains occur in two types, designated by the Greek letters kappa and lambda. Kappa and lambda light chains are approximately 250 amino acids in length with an average mass of about 25 kDa. The ratio of kappa to lambda found in the immunoglobulin population varies by species.

Immunogen

Epitope: Ig lambda light chain
Prepared from pooled antisera from goats hyperimmunized with human myeloma proteins with lambda light chains.

Physical form

Affinity Chromatography
Purified by affinity chromatography on pooled human Igs with lambda light chains covalently linked to agarose. Liquid in 50% glycerol/50% PBS, pH 7.4.

Preparation Note

Maintain refrigerated at 2°-8°C under sterile conditions for up to twelve months from date of receipt. For long term storage, aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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저장 등급

10 - Combustible liquids

wgk

WGK 2


시험 성적서(COA)

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문서 라이브러리 방문

Siqi Gong et al.
Antibodies (Basel, Switzerland), 11(2) (2022-06-02)
When constructing isogenic recombinant IgM-IgG pairs, we discovered that μ heavy chains strongly prefer partnering with λ light chains for optimal IgM expression in transiently cotransfected Expi293 cells. When μ chains were paired with κ light chains, IgM yields were
Jessica N Peel et al.
The Journal of clinical investigation, 134(8) (2024-03-12)
BACKGROUNDWeakly virulent environmental mycobacteria (EM) can cause severe disease in HLA-DRB1*15:02 or 16:02 adults harboring neutralizing anti-IFN-γ autoantibodies (nAIGAs). The overall prevalence of nAIGAs in the general population is unknown, as are the penetrance of nAIGAs in HLA-DRB1*15:02 or 16:02

국제 무역 품목 번호

SKUGTIN
AP506P04053252509735

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