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제품정보 (DICE 배송 시 비용 별도)
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
CY3 conjugate
Clone:
polyclonal
Application:
immunocytochemistry
immunofluorescence
immunohistochemistry
immunofluorescence
immunohistochemistry
Species reactivity:
mouse, rat
Citations:
3
Technique(s):
immunocytochemistry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
제품 이름
Neuro-Chrom Pan Neuronal Marker Antibody-Rabbit, Cy3 Conjugate, Neuro-Chrom, from rabbit
biological source
rabbit
conjugate
CY3 conjugate
clone
polyclonal
species reactivity
mouse, rat
manufacturer/tradename
Neuro-Chrom
technique(s)
immunocytochemistry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Analysis Note
Control
Rat E18 cortex primary neuron cell culture or mouse adult brain cryosections.
Rat E18 cortex primary neuron cell culture or mouse adult brain cryosections.
Routinely tested Rat E18 cortex primary neurons in Immunocytochemistry.
Application
Neuro-Chrom Pan Neuronal Marker-Rabbit, Cy3 Conjugate is an antibody targeting the Pan Neuronal Marker protein, validated for use in ICC, IHC & IF.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neuronal & Glial Markers
Neuronal & Glial Markers
Biochem/physiol Actions
Cat. # ABN2300C is specific to axons (neurites), dendrites, nucleus, and the cell body of neurons.
Reactivity with other species has not been determined.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Antibodies to neuronal proteins have become critical tools for identifying neurons and discerning morphological characteristics in culture and complex tissue. While the labeling from classic histological techniques such as Golgi staining and modern molecular approaches such as GFP constructs yield excellent cytoarchitectural detail, these approaches are technically challenging and impractical for many neuroscience research needs. Neuron-specific antibodies are convenient precision tools useful in revealing cytoarchitecture, but are limited to the protein target distribution within the neuron, which may differ greatly from nucleus to soma to dendrite and axon. To achieve as complete a morphological staining as possible across all parts of neurons, Millipore has developed a polyclonal antibody blend that reacts against key somatic, nuclear, dendritic, and axonal proteins distributed across the pan-neuronal architecture that can then be detected by a single secondary antibody. This antibody cocktail has been validated in diverse methods, cell culture and immuno-histochemistry, giving researchers a convenient and specific qualitative and quantitative tool for studying neuronal morphology.
Immunogen
Epitope: Whole Neuron Marker
Physical form
Polyclonal antibody cocktail blend conjugated to Cy3 in PBS buffer with 15mg/mL BSA and 0.05% NaN3
Preparation Note
Maintain at 2-8°C for up to 1 year from date of receipt.
저장 등급
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Paul S Baxter et al.
Cell reports, 34(12), 108882-108882 (2021-03-25)
Microglia, brain-resident macrophages, require instruction from the CNS microenvironment to maintain their identity and morphology and regulate inflammatory responses, although what mediates this is unclear. Here, we show that neurons and astrocytes cooperate to promote microglial ramification, induce expression of
Zoeb Jiwaji et al.
Nature communications, 13(1), 135-135 (2022-01-12)
Alzheimer's disease (AD) alters astrocytes, but the effect of Aß and Tau pathology is poorly understood. TRAP-seq translatome analysis of astrocytes in APP/PS1 ß-amyloidopathy and MAPTP301S tauopathy mice revealed that only Aß influenced expression of AD risk genes, but both
Cayla E Jewett et al.
eLife, 12 (2023-01-20)
Trisomy 21, the genetic cause of Down syndrome, disrupts primary cilia formation and function, in part through elevated Pericentrin, a centrosome protein encoded on chromosome 21. Yet how trisomy 21 and elevated Pericentrin disrupt cilia-related molecules and pathways, and the
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| ABN2300C3 | 04053252592409 |
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