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Merck

AB2253

Anti-Doublecortin Antibody

serum, from guinea pig

동의어(들):

Anti-Doublecortin Antibody, AB2253 | Sigma-Aldrich

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
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제품 이름

Anti-Doublecortin Antibody, serum, from guinea pig

biological source

guinea pig

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat, mouse

species reactivity (predicted by homology)

human (based on 100% sequence homology)

technique(s)

immunofluorescence: suitable (Frozen tissue sections)
immunohistochemistry: suitable (Paraffin)
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... DCDC1(341019)

Analysis Note

Control
Rat Brain lysate.
Evaluated by Western Blotting in rat brain tissue lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected Doublecortin in rat brain tissue lysate.

Application

Anti-Doublecortin Antibody has been used in immunohistochemistry and immunofluorescence staining.

Biochem/physiol Actions

Doublecortin (DCX) is identified as an important marker for neurogenesis. It serves as a valuable tool for studying and comparing the process of neurogenesis across different species.
Reactivity with other species has not been determined.
This Guinea pig polyclonal antibody detects doublecortin in murine and rat species. It targets an epitope with in 17 amino acids from the C-terminal region.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Anti-Doublecortin, Cat. No. AB2253, is a guinea pig polyclonal antibody that detects Doublecortin and is tested for use in Immunohistochemistry (Paraffin) and Immunofluorescence, and Western Blotting.
Target molecular weight ~42 kDa observed;40.61 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
~45 kDa observed; 40.57 kDa calculated. Uncharacterized bands may be observed in some lysate(s).

Immunogen

Epitope: C-Terminus
Recombinant Peptide.

Other Notes

Replaces: AB5910

Physical form

GST Depletion
GST-Depleted Guinea Pig Sera with 0.05% Sodium Azide

Preparation Note

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

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저장 등급

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Jacques Balthazart et al.
Brain, behavior and evolution, 84(1), 1-4 (2014-07-19)
Commentary on “Evaluating the Predictive Value of Doublecortin as a Marker for Adult Neurogenesis in Canaries (Serinus canaria)” by Michiel Vellema, Moritz Hertel, Susan L. Urbanus, Annemie Van der Linden, and Manfred Gahr (Journal of Comparative Neurology 2014, 522 :
Embryonic Nkx2. 1-expressing neural precursor cells contribute to the regional heterogeneity of adult V-SVZ neural stem cells
Delgado RN and Lim DA
Developmental Biology, 407(2), 265-274 (2015)
Tania Campos-Ordoñez et al.
Experimental neurology, 261, 236-244 (2014-05-27)
Hydrocephalus can develop secondarily to a disturbance in production, flow and/or absorption of cerebrospinal fluid. Experimental models of hydrocephalus, especially subacute and chronic hydrocephalus, are few and limited, and the effects of hydrocephalus on the subventricular zone are unclear. The
Combination treatment with ethyl pyruvate and IGF-I exerts neuroprotective effects against brain injury in a rat model of neonatal hypoxic-ischemic encephalopathy
Rong Z, et al.
International Journal of Molecular Medicine, 36(1), 195-203 (2015)
Hanadie Yousef et al.
Oncotarget, 6(14), 11959-11978 (2015-05-25)
Stem cell function declines with age largely due to the biochemical imbalances in their tissue niches, and this work demonstrates that aging imposes an elevation in transforming growth factor β (TGF-β) signaling in the neurogenic niche of the hippocampus, analogous

국제 무역 품목 번호

SKUGTIN
AB225304053252335495

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