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Merck

AB1954

Anti-Fibronectin Antibody

CHEMICON®, rabbit polyclonal

동의어(들):

Cold-insoluble globulin, fibronectin 1, migration stimulating factor, migration-stimulating factor

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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제품 이름

Anti-Fibronectin Antibody, Chemicon®, from rabbit

Quality Level

biological source

rabbit

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse, rat

packaging

antibody small pack of 25 μL

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
western blot: suitable

UniProt accession no.

shipped in

ambient

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

human ... FN1(2335)
mouse ... Fn1(14268)

관련 카테고리

Analysis Note

Control
Western Blot: Normal rat serum
Routinely evaluated by Western Blot on normal rat serum.

Western Blot Analysis:
0.05 μg/mL - 1 μg/mL antibody detected fibronectin in 15 μL of normal rat serum.

Application

Anti-Fibronectin Antibody detects level of Fibronectin & has been published & validated for use in ELISA & WB.
Research Category
Cell Structure
Research Sub Category
ECM Proteins

Biochem/physiol Actions

Other species have not been tested.
The antibody reacts with the 262 kDa fibronectin protein.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

262 kDa
Fibronectin (FN) is involved in many cellular processes, including tissue repair, embryogenesis, blood clotting, and cell migration/adhesion. Fibronectin exists in two main forms: 1) as an insoluble glycoprotein dimer that serves as a linker in the ECM (extracellular matrix), and; 2) as a soluble disulphide linked dimer found in the plasma (plasma FN). The plasma form is synthesized by hepatocytes, and the ECM form is made by fibroblasts, chondrocytes, endothelial cells, macrophages, as well as certain epithelial cells.

Immunogen

Purified rat plasma fibronectin.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Antigen Affinity Purified
Purified in 0.1M Tris-Glycine (pH7.4) 150mM NaCl with 0.05% NaN3.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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저장 등급

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


시험 성적서(COA)

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Rugmani Padmanabhan Iyer et al.
American journal of physiology. Heart and circulatory physiology, 311(3), H822-H836 (2016-08-16)
The purpose of this study was to evaluate the effect of sham surgery in a minimally invasive surgical model of permanent coronary artery occlusion used to generate myocardial infarction (MI) in mice. Adult male C57BL/6J mice (3-6 mo old) were
Cláudia Silva Souza et al.
Experimental biology and medicine (Maywood, N.J.), 244(9), 758-769 (2019-05-02)
To date, no studies have been found evaluating the effects of physical exercise on renal function and structure changes in ovariectomized rats with type 1 diabetes. Therefore, this work emerges with an important tool for strengthening and expanding innovative research
Ina V Martin et al.
American journal of physiology. Renal physiology, 314(1), F35-F46 (2017-09-15)
Complement factor C5a has two known receptors, C5aR, which mediates proinflammatory effects, and C5L2, a potential C5a decoy receptor. We previously identified C5a/C5aR signaling as a potent profibrotic pathway in the kidney. Here we tested for the first time the
Jialin Li et al.
Pharmaceutical biology, 60(1), 1690-1700 (2022-09-09)
Kirenol possesses anti-inflammatory, antifibrotic and anti-arthritic effects. However, its reno-protective effects against diabetic nephropathy (DN) have not been evaluated. This study explores the reno-protective effects of kirenol against DN and clarifies the potential mechanisms. The mesangial cells were treated with
Chao-Tang Chuang et al.
International journal of molecular medicine, 35(2), 546-552 (2014-12-09)
The advanced glycation end‑product (AGE)‑receptor for AGE (RAGE) axis induces transforming growth factor‑β (TGF‑β) expression, cell hypertrophy and increases extracellular matrices that are indicated in the pathogenesis of diabetic nephropathy (DN). RAGE binds to numerous ligands besides AGE, including S100B.

국제 무역 품목 번호

SKUGTIN
AB195404053252325403
AB1954-25UL04054839350481

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