492016
NP-40 Alternative
동의어(들):
NP-40 Alternative - CAS 9016-45-9 - Calbiochem, Nonylphenyl Polyethylene Glycol
SMILES string
O(CCOc1ccc(cc1)CCCCCCCCC)CCO
InChI
1S/C19H32O3/c1-2-3-4-5-6-7-8-9-18-10-12-19(13-11-18)22-17-16-21-15-14-20/h10-13,20H,2-9,14-17H2,1H3
InChI key
BLXVTZPGEOGTGG-UHFFFAOYSA-N
description
RTECS - MD0905000
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated
color
clear colorless
CMC
50 - 300 μM
solubility
water: 25 mg/mL
aqueous buffer: soluble
density
1.06 g/mL
application(s)
(Isolating membrane proteins)
shipped in
ambient
storage temp.
15-25°C
Quality Level
Disclaimer
Toxicity: Irritant (B)
General description
A non-ionic surfactant used in the isolation and purification of functional membrane protein complexes and in two-dimensional (2D) gel electrophoresis. Similar in usage to NP-40 and TRITON™ X-100 Detergent(Cat. No. 648462).
Other Notes
Ripoche, P., et al. 1982. Biochim. Biophys. Acta693, 497.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Triton is a trademark of The Dow Chemical Company or an affiliated company of Dow
Application
NP-40 Alternative has been used:
- as a component of the lysis buffer for solubilizing proteins from transfected HEK293 cells.
- as a component of the wash buffer for efficient solubilization of biotinylated plasma proteins in plasma protein profiling and chromatin immunoprecipitation (ChIP).
- for the purification of doublet microtubules from cilia for single particle cryo-electron microscopy (cryo-EM).
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2
저장 등급
11 - Combustible Solids
wgk
WGK 3
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Gustav Roder et al.
European journal of immunology, 39(10), 2682-2694 (2009-09-04)
Tapasin (Tpn) is an ER chaperone that is uniquely dedicated to MHC-I biosynthesis. It binds MHC-I molecules, integrates them into peptide-loading complexes, and exerts quality control of the bound peptides; only when an "optimal peptide" is bound will the MHC-I
Ju Gao et al.
Autophagy, 12(4), 632-647 (2016-04-07)
During proteasomal stress, cells can alleviate the accumulation of polyubiquitinated proteins by targeting them to perinuclear aggresomes for autophagic degradation, but the mechanism underlying the activation of this compensatory pathway remains unclear. Here we report that PINK1-s, a short form
Djihad Hadjadj et al.
Aging, 9(12), 2695-2716 (2017-12-29)
High proliferation rate and high mutation density are both indicators of poor prognosis in adrenocortical carcinomas. We performed a hypothesis-driven association study between clinical features in adrenocortical carcinomas and the expression levels of 136 genes involved in DNA metabolism and
Matthew R Miller et al.
Journal of biological methods, 2(3), e23-e23 (2015-10-13)
Over the past two decades, researchers have struggled to efficiently express foreign DNA in primary macrophages, impeding research progress. The applications of lipofection, electroporation, microinjection, and viral-mediated transfer typically result in disruptions in macrophage differentiation and function, low expression levels
Ying Zhang et al.
Cancer research, 79(19), 4994-5007 (2019-08-09)
Human astrocytomas and oligodendrogliomas are defined by mutations of the metabolic enzymes isocitrate dehydrogenase (IDH) 1 or 2, resulting in the production of the abnormal metabolite D-2 hydroxyglutarate. Here, we studied the effect of mutant IDH on cell proliferation and
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 492016-500MLCN | 04055977273496 |
| 492016-1000MLCN | 04055977273489 |
| 492016-100MLCN | 07790788050832 |
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