361548
GSK-3β Inhibitor VII
The GSK-3β Inhibitor VII, also referenced under CAS 99-73-0, controls the biological activity of GSK-3β. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
동의어(들):
GSK-3β Inhibitor VII, α-4-Dibromoacetophenone, TPK I Inhibitor, Tau Protein Kinase I Inhibitor
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C8H6Br2O
CAS 번호:
Molecular Weight:
277.94
UNSPSC Code:
12352100
NACRES:
NA.77
MDL number:
Assay:
≥95% (HPLC)
Form:
solid
Quality level:
Storage condition:
OK to freeze, desiccated, protect from light
SMILES string
BrCC(=O)c1ccc(cc1)Br
InChI
1S/C8H6Br2O/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4H,5H2
InChI key
FKJSFKCZZIXQIP-UHFFFAOYSA-N
description
RTECS - AM6950000
assay
≥95% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated, protect from light
color
white
solubility
DMSO: 5 mg/mL
shipped in
wet ice
storage temp.
−20°C
Quality Level
General description
A phenyl α-bromomethyl ketone compound that acts as a cell-permeable, and non-ATP competitive inhibitor of GSK-3β (IC50 = 0.5 µM). This reactive alkylating agent is selective towards GSK-3β and does not affect PKA activity even at concentrations as high as 100 µM.
Biochem/physiol Actions
Cell permeable: yes
Product does not compete with ATP.
Reversible: no
Target IC50: 0.5 µM against GSK-3β
Packaging
Packaged under inert gas
Other Notes
Conde, S., et al. 2003. J. Med. Chem.46, 4631.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
signalword
Danger
hcodes
Hazard Classifications
Skin Corr. 1B
저장 등급
8A - Combustible corrosive hazardous materials
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 361548-5MGCN | 04055977214048 |
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