Tryptic Soy Broth with Neutralizers

Tryptic Soy Broth with neutralizers is suitable for the isolation and cultivation of aerobic and facultative anaerobic bacteria, yeasts, and molds in the presence of disinfectant residues. The medium is used for the testing of sterile and non-sterile substances, preparations, and products.

Our ready to use media provide the highest level of quality and testing confidence. They have been formulated and tested to meet the pharmacopoeia requirements. Sterility testing media and rinse solutions are manufactured in an ISO 9001, environmentally controlled production center. Each lot undergoes a stringent quality control (QC) procedure, including pH, sterility and growth promotion tests. Our manufacturing approach ensures the highest level of clarity for our media and rinsing fluids, therefore improving accuracy and significantly reducing the risk of incorrect interpretation and false results.

Tryptic Soy Broth is a highly nutritious, universal complex medium and hence supports the growth of a wide variety of aerobic and facultative anaerobic microorganisms, including fungi. The neutralizing additives polysorbate (Tween^®) 80, sodium thiosulfate, cysteine, histidine, and lecithin reverse the growth inhibitory effect of most disinfectants and antiseptics. Histidine has neutralizing efficiency against formaldehyde and formaldehyde-releasing agents. Sodium thiosulfate inactivates sodium hypochlorite and acidified sodium chlorite. Cysteine is a reducing agent that neutralizes the oxidizing agents such as hydrogen peroxide and iodine. Lecithin, particularly in combination with Polysorbate 80, is effective against quaternary ammonium compounds, amphoteric surfactants, benzamidines, chlorhexidines, and dequadin. Polysorbate 80 inactivates benzyl alcohol, carbanilides, dichlorbenzyl alcohols, benzoic acid, p-hydroxybenzoic acid, and its esters, phenols, phenylethyl alcohols, and Solbrols (PHB esters).

TWEEN is a registered trademark of Croda International PLC