제품 이름
Superspher® 60 RP-select B LiChroCART™ 75-4, suitable for HPLC
material
stainless steel column
Quality Segment
agency
suitable for USP L7
product line
Superspher®
feature
endcapped: no
parameter
250 bar pressure, 60 °C max. temp.
technique(s)
HPLC: suitable, mass spectrometry (MS): suitable (Low - Medium)
column L × I.D.
7.5 cm × 4 mm
matrix
fully porous particle
matrix active group
C8 (RP8), C8 bonding phase
particle size
4 μm
pore size
60 Å pore size
operating pH range
2-7.5
separation technique
reversed phase
storage temp.
no temp limit
General description
HPLC cartridge
Superspher® RP-select B is a highly reproducible traditionally produced spherical silica gel carriers with reversed phase properties and the hydrophobicity of a C-8 phase. This carrier is very well suited for the separation of basic compounds, but with still good properties for the determination of neutral and acidic compounds. The high performance silica carrier with a particle size of 4µm yields an excellent pressure/separation performance ratio.This sorbent is packed into a LiChroCART 75-4 HPLC cartridge. The connection to the HPLC system is being accomplished by use of the manu-CART NT cartrige holder (1.51486).
Application
- Screening, library-assisted identification and validated quantification of 23 benzodiazepines, flumazenil, zaleplone, zolpidem and zopiclone in plasma: This study demonstrates the application of liquid chromatography/mass spectrometry with atmospheric pressure chemical ionization for the screening and quantification of various compounds in plasma, utilizing the high-resolution capabilities of the Superspher 60 RP-select B column (Kratzsch et al., 2004).
- Screening, library-assisted identification and validated quantification of fifteen neuroleptics and three of their metabolites in plasma: Employing liquid chromatography/mass spectrometry with atmospheric pressure chemical ionization, this study utilized the Superspher 60 RP-select B to detect and quantify neuroleptics in plasma, showcasing its utility in pharmaceutical and clinical research (Kratzsch et al., 2003).
- Validated assay for quantification of oxcarbazepine and its active dihydro metabolite 10-hydroxycarbazepine in plasma: This research highlights the column′s application in therapeutic drug monitoring using atmospheric pressure chemical ionization liquid chromatography/mass spectrometry, reflecting its precision and reliability in clinical pharmacology (Maurer et al., 2002).
Analysis Note
Pressure: ≤ 50 bar
Theoretical Plates (N/m) (1,2-Benzanthracene): ≥ 85000
Symmetry (1,2-Benzanthracene): 0.8 - 1.4
Capacity factor (1,2-Benzanthracene): ≥ 2.5
Theoretical Plates (N/m) (1,2-Benzanthracene): ≥ 85000
Symmetry (1,2-Benzanthracene): 0.8 - 1.4
Capacity factor (1,2-Benzanthracene): ≥ 2.5
Legal Information
LICHROCART is a trademark of Merck KGaA, Darmstadt, Germany
Superspher is a registered trademark of Merck KGaA, Darmstadt, Germany
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시험 성적서(COA)
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국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 1.50974.0001 | 04022536234021 |