수량	카탈로그 번호	주문 설명	포장 단위	기재 가격
			96-Well Plate

수량	카탈로그 번호	주문 설명	포장 단위	기재 가격
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

567021 Sigma-AldrichSimvastatin, Sodium Salt - Calbiochem

Simvastatin, Sodium Salt is a carboxylate form of Simvastatin. Active in whole cells and in cell-free preparations. An inhibitor of HMG-CoA reductase.

Simvastatin, Sodium Salt - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

CoA
References
Data Sheet

Synonyms: L-Type Calcium Channel Blocker VI

Primary Target: 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase

Recommended Products

개요

Replacement Information

주요 사양표

Empirical Formula
C₂₅H₃₉O₆ • Na

가격 및 재고여부

카탈로그 번호	재고 정보	패킹	포장 단위	가격(VAT 별도)	수량
567021-50MGCN	재고 정보 검색... — 현재 재고 없음 예상 출고 가능일 단종품 제한된 수량 가능 재고여부 확인 재고목록을 보려면 로그인하십시오 예상 출고 가능일 현재 재고 없음 예상 출고 가능일 Remaining: will advise Remaining: will advise 추천사항 고객 서비스로 문의 Contact Customer Service 고객 서비스로 문의 고객 서비스로 문의	Glass bottle	50 mg	가격 검색... 가격을 검색할 수 없습니다 Minimum Quantity needs to be mulitiple of Maximum Quantity is 가격 문의 추가 정보 ()이 할인됨 — 가격 문의 고객님의 가격을 보려면 로그인하십시오	재고 조회 —	즐겨찾기에 추가 즐겨찾기에 추가 나의 즐겨찾기에 추가
567021-5MGCN	재고 정보 검색... — 현재 재고 없음 예상 출고 가능일 단종품 제한된 수량 가능 재고여부 확인 재고목록을 보려면 로그인하십시오 예상 출고 가능일 현재 재고 없음 예상 출고 가능일 Remaining: will advise Remaining: will advise 추천사항 고객 서비스로 문의 Contact Customer Service 고객 서비스로 문의 고객 서비스로 문의	Plastic ampoule	5 mg	가격 검색... 가격을 검색할 수 없습니다 Minimum Quantity needs to be mulitiple of Maximum Quantity is 가격 문의 추가 정보 ()이 할인됨 — 가격 문의 고객님의 가격을 보려면 로그인하십시오	재고 조회 —	즐겨찾기에 추가 즐겨찾기에 추가 나의 즐겨찾기에 추가

Description
Overview	Carboxylate form of Simvastatin (Cat. No. 567020) that is active in whole cells and in cell-free preparations. Also available as a 10 mM solution in H₂O (Cat. No. 567022).
Catalogue Number	567021
Brand Family	Calbiochem®
Synonyms	L-Type Calcium Channel Blocker VI

References
References	Yada, T., et al. 1999. Br. J. Pharmacol. 126, 1205. Clutterbuck, R.D., et al. 1998. Br. J. Haematol. 102, 522. Yokoyama, K., et al. 1998. Mol. Biochem. Parasitol. 94, 87. Negre-Aminou, P., et al. 1997. Biochim. Biophys. Acta 1345, 259. Vrtovsnik, F., et al. 1997. Kidney Int. 52, 1016. Keyomarsi, K., et al. 1991. Cancer Res. 51, 3602.

Product Information
ATP Competitive	N
Form	Beige solid
Hill Formula	C₂₅H₃₉O₆ • Na
Chemical formula	C₂₅H₃₉O₆ • Na
Hygroscopic	Hygroscopic
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase
Purity	≥97% by HPLC

Physicochemical Information
Cell permeable	Y

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
카탈로그 번호	GTIN
567021-50MGCN	04055977267112
567021-5MGCN	07790788051587

Documentation

Simvastatin, Sodium Salt - Calbiochem Certificates of Analysis

Title	Lot Number
567021	로트(lot) 번호를 입력하십시오.

References

참고문헌 보기
Yada, T., et al. 1999. Br. J. Pharmacol. 126, 1205. Clutterbuck, R.D., et al. 1998. Br. J. Haematol. 102, 522. Yokoyama, K., et al. 1998. Mol. Biochem. Parasitol. 94, 87. Negre-Aminou, P., et al. 1997. Biochim. Biophys. Acta 1345, 259. Vrtovsnik, F., et al. 1997. Kidney Int. 52, 1016. Keyomarsi, K., et al. 1991. Cancer Res. 51, 3602.

Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	13-October-2015 JSW
Synonyms	L-Type Calcium Channel Blocker VI
Description	Carboxylate form of Simvastatin (Cat. No. 567020) that is active in whole cells and in cell-free assays. A lipophilic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that blocks Ras function through inhibition of farnesylation. Also inhibits glucose-induced Ca²⁺-signaling and insulin secretion by blocking L-type Ca²⁺ channels in rat islet β-cells. Inhibits cell proliferation of human smooth muscle cells. Note: This product is supplied in an active form; no treatment with NaOH in ethanol is required for its activation.
Form	Beige solid
Intert gas (Yes/No)	Packaged under inert gas
Chemical formula	C₂₅H₃₉O₆ • Na
Structure formula
Purity	≥97% by HPLC
Solubility	DMSO (100 mg/ml), Ethanol (25 mg/ml), or H₂O (5 mg/ml)
Storage	-20°C Hygroscopic
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Toxicity	Standard Handling
References	Yada, T., et al. 1999. Br. J. Pharmacol. 126, 1205. Clutterbuck, R.D., et al. 1998. Br. J. Haematol. 102, 522. Yokoyama, K., et al. 1998. Mol. Biochem. Parasitol. 94, 87. Negre-Aminou, P., et al. 1997. Biochim. Biophys. Acta 1345, 259. Vrtovsnik, F., et al. 1997. Kidney Int. 52, 1016. Keyomarsi, K., et al. 1991. Cancer Res. 51, 3602.

카테고리

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Lipid Signaling Inhibitors > HMG-CoA (3-Hydroxy-3-Methylglutaryl Coenzyme A) Reductase Inhibitors

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