03-0177-00
SMC® Human IL-17A/F Heterodimer High Sensitivity Immunoassay Kit
Used for ultrasensitive quantification of Human IL-17A/F Heterodimer in human serum and plasma
동의어(들):
IL-17A/F Single Molecule Counting Kit, IL-17A/F ultra-sensitive immunoassay
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크기 선택
보기 변경
제품정보 (DICE 배송 시 비용 별도)
NACRES:
NA.84
UNSPSC Code:
12161503
Species reactivity:
human
Technique(s):
single molecule counting: suitable
Usage:
kit sufficient for 96 wells
Compatibility:
for use with TM="FemtoQuest"] and SMCxPRO® instruments
제품 이름
SMC® Human IL-17A/F Heterodimer High Sensitivity Immunoassay Kit,
description
Used for ultrasensitive quantification of Human IL-17A/F Heterodimer in human serum and plasma
product line
SMC®
usage
kit sufficient for 96 wells
species reactivity
human
technique(s)
single molecule counting: suitable
input
serum
plasma (K2 EDTA)
UniProt accession no.
compatibility
for use with TM="FemtoQuest"] and SMCxPRO® instruments
shipped in
wet ice
storage temp.
2-8°C
General description
Interleukin-17A/F (IL-17A/F) is a heterodimeric cytokine formed by the combination of IL-17A and IL-17F subunits, both of which are produced primarily by Th17 cells. This cytokine plays a significant role in mediating inflammatory responses and is involved in the recruitment of neutrophils and other immune cells to sites of inflammation. IL-17A/F is implicated in various autoimmune diseases and chronic inflammatory conditions, highlighting its potential as a therapeutic target for managing such disorders.
Application
Inflammatory Disease / Immune Response / Autoimmune Disease
Features and Benefits
- Specific Detection of IL-17A/F Heterodimer: Enables accurate quantification of the biologically distinct IL-17A/F complex, which plays a unique role in Th17-mediated inflammation and autoimmune disease.
- Ultra-Sensitive Quantification via SMC®Technology: Supports early detection of immune activation, especially in diseases where IL-17A/F is present at low levels, such as psoriasis, multiple sclerosis, and IBD.
- Verified for Human Serum and Plasma: Demonstrates high recovery rates (88–101%) in spiked human samples.
Packaging
96 well assay
Analysis Note
- Sensitivity: LLOQ 2,340 fg/mL* (SMCxPRO® Instrument)
- Standard Curve Range: 590-600,000 fg/mL
- Intra-assay CV: <15%
- Inter-assay CV: <20%
- Linearity: Serum: 106% Plasma: 111%
- Recovery: Serum: 101% Plasma: 88%
Other Notes
Although IL-17A/F Heterodimer was detectable in non-human primates, monkey and canine samples, the assay has not been verified for these species.
Legal Information
SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
signalword
Danger
저장 등급
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - ED ENV 1 - Eye Irrit. 2 - Repr. 1B
시험 성적서(COA)
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