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566325 SIRT1 Inhibitor IV, (S)-35 - CAS 848193-72-6 - Calbiochem

SIRT1 Inhibitor IV, (S)-35, CAS 848193-72-6, is a cell-permeable, entiomerically pure compound that displays similar potency (IC50 = 63 nM) and selectivity as SIRT1 Inhibitor III (Cat. No. 566322).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (6S)-2-Chloro-5,6,7,8,9,10-hexahydro-cyclohepta[b]indole-6-carboxamide

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566325
가격 및 재고 조회

개요

Replacement Information

주요 사양표

CAS #Empirical Formula
848193-72-6C₁₄H₁₅ClN₂O

가격 및 재고여부

카탈로그 번호 재고 정보패킹 포장 단위 가격(VAT 별도) 수량
566325-500UGCN
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      		 Plastic ampoule 500 μg
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      Description
      OverviewA cell-permeable entiomerically pure compound that is structurally similar to and exhibits similar potency (IC50 = 63 nM) and selectivity as SIRT1 Inhibitor III (Cat. No. 566322). Shown to be orally bioavailable with a serum half-life of 94 min in mice in vivo.
      Catalogue Number566325
      Brand Family Calbiochem®
      Synonyms(6S)-2-Chloro-5,6,7,8,9,10-hexahydro-cyclohepta[b]indole-6-carboxamide
      Application Data
      References
      ReferencesNapper, A.D., et al. 2005. J. Med. Chem. 48, 8045.
      Product Information
      CAS number848193-72-6
      FormOff-white solid
      Hill FormulaC₁₄H₁₅ClN₂O
      Chemical formulaC₁₄H₁₅ClN₂O
      Quality LevelMQ100
      Applications
      ApplicationSIRT1 Inhibitor IV, (S)-35, CAS 848193-72-6, is a cell-permeable, entiomerically pure compound that displays similar potency (IC50 = 63 nM) and selectivity as SIRT1 Inhibitor III (Cat. No. 566322).
      Biological Information
      Purity≥96% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 22-36/37/38

      Harmful if swallowed.
      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26-36-45

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      카탈로그 번호 GTIN
      566325-500UGCN 04055977191424

      Documentation

      SIRT1 Inhibitor IV, (S)-35 - CAS 848193-72-6 - Calbiochem MSDS

      타이틀

      물질안전보건자료(MSDS) 

      SIRT1 Inhibitor IV, (S)-35 - CAS 848193-72-6 - Calbiochem Certificates of Analysis

      TitleLot Number
      566325

      References

      참고문헌 보기
      Napper, A.D., et al. 2005. J. Med. Chem. 48, 8045.

      Data Sheet

      Title
      SIRTainty™ Class III HDAC Assay
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision01-April-2009 RFH
      Synonyms(6S)-2-Chloro-5,6,7,8,9,10-hexahydro-cyclohepta[b]indole-6-carboxamide
      Application Data
      DescriptionA cell-permeable entiomerically pure compound that is structurally similar to and exhibits similar potency (IC50 = 63 nM) and selectivity as SIRT1 Inhibitor III (Cat. No. 566322). Shown to be orally bioavailable with a serum half-life of 94 minutes in mice in vivo.
      FormOff-white solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number848193-72-6
      Chemical formulaC₁₄H₁₅ClN₂O
      Purity≥96% by HPLC
      SolubilityDMSO (10 mg/ml) or Ethanol (5 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Harmful
      ReferencesNapper, A.D., et al. 2005. J. Med. Chem. 48, 8045.