516481 Sigma-AldrichPepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem
Pepstatin A, Synthetic, CAS 26305-03-3, is a reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin.
More>> Pepstatin A, Synthetic, CAS 26305-03-3, is a reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: Iva-Val-Val-Sta-Ala-Sta, Isovaleryl-Val-Val-4-amino-3-hydroxy-6-methylheptanoyl-Ala-4-amino-3-hydroxy-6-methylheptanoic Acid
Recommended Products
개요
| Replacement Information |
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주요 사양표
| CAS # | Empirical Formula |
|---|---|
| 26305-03-3 | C₃₄H₆₃N₅O₉ |
가격 및 재고여부
| 카탈로그 번호 | 재고 정보 | 패킹 | 포장 단위 | 가격(VAT 별도) | 수량 | |
|---|---|---|---|---|---|---|
| 516481-100MGCN |
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Plastic ampoule | 100 mg |
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| 516481-25MGCN |
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Plastic ampoule | 25 mg |
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| 516481-5MGCN |
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Plastic ampoule | 5 mg |
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| Description | |
|---|---|
| Overview | A reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin. Reported to block apoptosis induced by CA-074 (Cat. No. 205530) in PC12 cell lines. Also available as a 25 mM solution in DMSO (Cat. No. 508437). |
| Effective concentration: 1.0 µM. | |
| Catalogue Number | 516481 |
| Brand Family | Calbiochem® |
| Synonyms | Iva-Val-Val-Sta-Ala-Sta, Isovaleryl-Val-Val-4-amino-3-hydroxy-6-methylheptanoyl-Ala-4-amino-3-hydroxy-6-methylheptanoic Acid |
| Product Information | |
|---|---|
| CAS number | 26305-03-3 |
| ATP Competitive | N |
| Form | White solid |
| Hill Formula | C₃₄H₆₃N₅O₉ |
| Chemical formula | C₃₄H₆₃N₅O₉ |
| Optical rotation | Optical rotation: -90.0 ± 5° (c = 0.5, MeOH, 20°C). |
| Reversible | Y |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
|---|---|
| Primary Target | cathepsin D |
| Primary Target IC<sub>50</sub> | EC50 = 1.0 µM in blocking apoptosis induced by CA-074 in PC12 cell lines |
| Purity | ≥98% by HPLC |
| Physicochemical Information | |
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| Cell permeable | N |
| Dimensions |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS | |
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| RTECS | SC6155000 |
| Safety Information |
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| Product Usage Statements |
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| Packaging Information |
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| Transport Information |
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| Supplemental Information |
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| Specifications |
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| Global Trade Item Number | |
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| 카탈로그 번호 | GTIN |
| 516481-100MGCN | 04055977198812 |
| 516481-25MGCN | 07790788055837 |
| 516481-5MGCN | 04055977198836 |
Documentation
Pepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem MSDS
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Pepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 516481 |
References
| 참고문헌 보기 |
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| Isahara, K., et al. 1999. Neuroscience 91, 233. Kanamori, S., et al. 1998. Biochem. Biophys. Res. Commun. 251, 204. Szewczuk, Z., et al. 1992. Int. J. Pept. Prot. Res. 40, 233. Carraway, R.E., et al. 1991. Peptides 12, 107. Eid, M., et al. 1981. Biochem. J. 197, 465. Umezawa, H., et al. 1970. J. Antibiot. 23, 259. |
Brochure
| Title |
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| Western Blotting Tools |
Technical Info
| Title |
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| Protein Blotting Handbook: 6th Edition |