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539624 PKCζ Pseudosubstrate Inhibitor, Myristoylated - Calbiochem

PKCζ Pseudosubstrate Inhibitor is a myristoylated, cell-permeable, reversible, substrate competitive inhibitor of protein kinase Cζ.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Myr-SIYRRGARRWRKL-OH, Protein Kinase Cζ Pseudosubstrate Inhibitor, Myristoylated

Primary Target: insulin-stimulated transport in intact adinocytes
539624
가격 및 재고 조회

개요

Replacement Information

주요 사양표

Empirical Formula
C₉₀H₁₅₄N₃₀O₁₇

가격 및 재고여부

카탈로그 번호 재고 정보패킹 포장 단위 가격(VAT 별도) 수량
539624-500UGCN
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      		 Glass bottle 500 μg
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      Description
      OverviewA cell-permeable, reversible, substrate competitive, myristoylated form of the protein kinase Cζ isozyme pseudosubstrate inhibitory (Cat. No. 539610).
      Catalogue Number539624
      Brand Family Calbiochem®
      SynonymsMyr-SIYRRGARRWRKL-OH, Protein Kinase Cζ Pseudosubstrate Inhibitor, Myristoylated
      References
      ReferencesPowell, D.J., et al. 2003. Mol. Cell Biol. 23, 7794.
      Sajan, M.P., et al. 1999. J. Biol. Chem. 274, 30495.
      Standaert, M.L., et al. 1999. J. Biol. Chem. 274, 14074.
      Laudanna, C., et al. 1998. J. Biol. Chem. 273, 30306.
      Standaert, M.L., et al. 1997. J. Biol. Chem. 272, 30075.
      Product Information
      ATP CompetitiveN
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₉₀H₁₅₄N₃₀O₁₇
      Chemical formulaC₉₀H₁₅₄N₃₀O₁₇
      Hygroscopic Hygroscopic
      ReversibleY
      Sold on the basis of peptide contentY
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetinsulin-stimulated transport in intact adinocytes
      Primary Target IC<sub>50</sub>EC50 = 10-20 µM against insulin-stimulated transport in intact adipocytes
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableY
      Peptide ContentY
      Peptide SequenceMyr-Ser-Ile-Tyr-Arg-Arg-Gly-Ala-Arg-Arg-Trp-Arg-Lys-Leu-OH
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      카탈로그 번호 GTIN
      539624-500UGCN 04055977194791

      Documentation

      PKCζ Pseudosubstrate Inhibitor, Myristoylated - Calbiochem Certificates of Analysis

      TitleLot Number
      539624

      References

      참고문헌 보기
      Powell, D.J., et al. 2003. Mol. Cell Biol. 23, 7794.
      Sajan, M.P., et al. 1999. J. Biol. Chem. 274, 30495.
      Standaert, M.L., et al. 1999. J. Biol. Chem. 274, 14074.
      Laudanna, C., et al. 1998. J. Biol. Chem. 273, 30306.
      Standaert, M.L., et al. 1997. J. Biol. Chem. 272, 30075.

      Citations

      타이틀
    • Fishelevich, R., et al. 2006. Journal of Immunology 176, 2590.
    • Mason, J.C., et al. 2004. Journal of Biological Chemistry 279, 41611.
      		•
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision11-January-2010 RFH
      SynonymsMyr-SIYRRGARRWRKL-OH, Protein Kinase Cζ Pseudosubstrate Inhibitor, Myristoylated
      DescriptionA cell-permeable, reversible, substrate competitive myristoylated form of protein kinase Cζ pseudo-substrate peptide (Cat. No. 539610) that includes amino acids 113-125 of the pseudosubstrate region. Useful for inhibition studies of PKCζ in intact cells. Reported to inhibit insulin-stimulated glucose transport in intact adipocytes (EC50 = 10-20 µM).
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Chemical formulaC₉₀H₁₅₄N₃₀O₁₇
      Peptide SequenceMyr-Ser-Ile-Tyr-Arg-Arg-Gly-Ala-Arg-Arg-Trp-Arg-Lys-Leu-OH
      Purity≥97% by HPLC
      SolubilityH₂O (2 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesPowell, D.J., et al. 2003. Mol. Cell Biol. 23, 7794.
      Sajan, M.P., et al. 1999. J. Biol. Chem. 274, 30495.
      Standaert, M.L., et al. 1999. J. Biol. Chem. 274, 14074.
      Laudanna, C., et al. 1998. J. Biol. Chem. 273, 30306.
      Standaert, M.L., et al. 1997. J. Biol. Chem. 272, 30075.
      Citation
    • Fishelevich, R., et al. 2006. Journal of Immunology 176, 2590.
    • Mason, J.C., et al. 2004. Journal of Biological Chemistry 279, 41611.
      		•