Millipore Sigma Vibrant Logo

616387 Nα-Tosyl-Phe Chloromethyl Ketone

View Products on Sigmaaldrich.com
616387
가격 및 재고 조회

개요

Replacement Information

주요 사양표

CAS #Empirical Formula
402-71-1C₁₇H₁₈ClNO₃S

가격 및 재고여부

카탈로그 번호 재고 정보패킹 포장 단위 가격(VAT 별도) 수량
616387-250MGCN
재고 정보 검색...
현재 재고 없음
현재 재고 없음
예상 출고 가능일 
단종품
제한된 수량 가능
재고여부 확인
    Remaining: will advise
      Remaining: will advise
      추천사항
      고객 서비스로 문의
      Contact Customer Service

      Plastic ampoule 250 mg
      가격 검색...
      가격을 검색할 수 없습니다
      Minimum Quantity needs to be mulitiple of
      Maximum Quantity is
      가격 문의 추가 정보
      ()이 할인됨
       
      가격 문의
      Description
      Overview

      This product has been discontinued.





      Irreversible inhibitor of chymotrypsin. Useful for inhibiting chymotrypsin activity in trypsin preparations. Inhibits apoptosis in thymocytes. Blocks the induction of nitric oxide synthase by γ-interferon and lipopolysaccharides (EC50 = 20 µM).
      Catalogue Number616387
      Brand Family Calbiochem®
      SynonymsTPCK
      References
      ReferencesFearnhead, H.O., et al. 1995. FEBS Lett. 357, 242.
      Griscavage, J.M., et al. 1995. Biochem. Biophys. Res. Commun. 215, 721.
      Weaver, V.M., et al. 1993. Biochem. Cell Biol. 71, 488.
      Murakami, T., et al. 1991. Biochim. Biophys. Acta 1079, 279.
      Nierodzik, M.L., et al. 1991. J. Clin. Invest. 87, 229.
      Wilson, W.E., et al. 1989. J. Biol. Chem. 264, 17777.
      Product Information
      CAS number402-71-1
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₁₇H₁₈ClNO₃S
      Chemical formulaC₁₇H₁₈ClNO₃S
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetchymotrypsin activity in preparations
      Primary Target IC<sub>50</sub>EC50 = 20 µM in blocking the induction of nitric oxide synthase by γ-interferon and lipopolysaccharides.
      Purity≥98% by TLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSXT5613500
      Safety Information
      R PhraseR: 41

      Risk of serious damage to eyes.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 4 months at 4°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      카탈로그 번호 GTIN
      616387-250MGCN 04055977186314

      Documentation

      Nα-Tosyl-Phe Chloromethyl Ketone MSDS

      타이틀

      물질안전보건자료(MSDS) 

      Nα-Tosyl-Phe Chloromethyl Ketone Certificates of Analysis

      TitleLot Number
      616387

      References

      참고문헌 보기
      Fearnhead, H.O., et al. 1995. FEBS Lett. 357, 242.
      Griscavage, J.M., et al. 1995. Biochem. Biophys. Res. Commun. 215, 721.
      Weaver, V.M., et al. 1993. Biochem. Cell Biol. 71, 488.
      Murakami, T., et al. 1991. Biochim. Biophys. Acta 1079, 279.
      Nierodzik, M.L., et al. 1991. J. Clin. Invest. 87, 229.
      Wilson, W.E., et al. 1989. J. Biol. Chem. 264, 17777.

      Citations

      타이틀
    • Ok Hee Ryu, et al. (2005) Proteolysis of MIP-1α isoforms LD78β and LD78α by neutrophil-derived serine proteases. Journal of Biological Chemistry 280, 17415-17421.
    • Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-September-2008 RFH
      SynonymsTPCK
      DescriptionIrreversible inhibitor of chymotrypsin. Useful for inhibiting chymotrypsin activity in trypsin preparations. Inhibits apoptosis in thymocytes. Blocks the induction of nitric oxide synthase by γ-interferon and lipopolysaccharide (EC50 = 20 µM). Suggested working concentration is 10-100 µM.
      FormWhite solid
      CAS number402-71-1
      RTECSXT5613500
      Chemical formulaC₁₇H₁₈ClNO₃S
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityEthanol (5 mg/ml) or Methanol (5 mg/ml)
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 4 months at 4°C.
      Toxicity Irritant
      ReferencesFearnhead, H.O., et al. 1995. FEBS Lett. 357, 242.
      Griscavage, J.M., et al. 1995. Biochem. Biophys. Res. Commun. 215, 721.
      Weaver, V.M., et al. 1993. Biochem. Cell Biol. 71, 488.
      Murakami, T., et al. 1991. Biochim. Biophys. Acta 1079, 279.
      Nierodzik, M.L., et al. 1991. J. Clin. Invest. 87, 229.
      Wilson, W.E., et al. 1989. J. Biol. Chem. 264, 17777.
      Citation
    • Ok Hee Ryu, et al. (2005) Proteolysis of MIP-1α isoforms LD78β and LD78α by neutrophil-derived serine proteases. Journal of Biological Chemistry 280, 17415-17421.