Millipore Sigma Vibrant Logo

475984 MyoVin-1 - CAS 1259177-59-7 - Calbiochem

A pyrazolopyrimidine compound that blocks ADP release from the actomyosin complex and acts as a potent, reversible and uncompetitive inhibitor of actin-stimulated ATPase activity of myosin V.

MyoVin-1 - CAS 1259177-59-7 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Myosin V Inhibitor 1

View Products on Sigmaaldrich.com
475984
가격 및 재고 조회

개요

Replacement Information

가격 및 재고여부

카탈로그 번호 재고 정보패킹 포장 단위 가격(VAT 별도) 수량
475984-5MGCN
재고 정보 검색...
—
현재 재고 없음 현재 재고 없음
예상 출고 가능일 
단종품
제한된 수량 가능
재고여부 확인
    Remaining: will advise
      Remaining: will advise
      추천사항
      고객 서비스로 문의
      Contact Customer Service

      		 Glass bottle 5 mg
      가격 검색...
      가격을 검색할 수 없습니다
      Minimum Quantity needs to be mulitiple of
      Maximum Quantity is
      가격 문의 추가 정보
      ()이 할인됨
       
      —
      가격 문의
      		 —
      Description
      OverviewA pyrazolopyrimidine compound that blocks ADP release from the actomyosin complex and acts as a potent, reversible and uncompetitive inhibitor of actin-stimulated ATPase activity of myosin V (Ki = 6.3 and 5.5 µM by single- and double-headed myosin V). Displays excellent selectivity over myosin II and myosin IV (< 10 % inhibition at 50 µM) and only minimally inhibits the kinase activity of Cdk1/B, CHK1, Plk1, Abl, ERK2, CKII and Aurora-B (< 10 % inhibition at 100 µM).
      Catalogue Number475984
      Brand Family Calbiochem®
      SynonymsMyosin V Inhibitor 1
      References
      ReferencesIslam, K., et al. 2010. Angew. Chem. Int. Ed. 49, 8484.
      Product Information
      CAS number1259177-59-7
      FormPale yellow powder
      Hill FormulaC₂₉H₂₆N₆O₃S
      Chemical formulaC₂₉H₂₆N₆O₃S
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      카탈로그 번호 GTIN
      475984-5MGCN 04055977184372

      Documentation

      MyoVin-1 - CAS 1259177-59-7 - Calbiochem MSDS

      타이틀

      물질안전보건자료(MSDS) 

      MyoVin-1 - CAS 1259177-59-7 - Calbiochem Certificates of Analysis

      TitleLot Number
      475984

      References

      참고문헌 보기
      Islam, K., et al. 2010. Angew. Chem. Int. Ed. 49, 8484.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision30-November-2012 JSW
      SynonymsMyosin V Inhibitor 1
      DescriptionA pyrazolopyrimidine compound that blocks ADP release from the actomyosin complex and acts as a potent, reversible and uncompetitive inhibitor of actin-stimulated ATPase activity of myosin V (Ki = 6.3 and 5.5 µM by single- and double-headed myosin V). Displays excellent selectivity over myosin II and myosin IV (< 10 % inhibition at 50 µM) and only minimally inhibits the kinase activity of Cdk1/B, CHK1, Plk1, Abl, ERK2, CKII and Aurora-B (< 10 % inhibition at 100 µM).
      FormPale yellow powder
      Intert gas (Yes/No) Packaged under inert gas
      CAS number1259177-59-7
      Chemical formulaC₂₉H₂₆N₆O₃S
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMSO (50 mg/ml)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesIslam, K., et al. 2010. Angew. Chem. Int. Ed. 49, 8484.