Millipore Sigma Vibrant Logo

23-054 MuRF1 Protein, active, 10 µg

Active, full length, recombinant human MuRF1. N-terminal GST-tagged. For use in Enzyme Assays. Functions as an E3 ligase in ubiquitination assays.

MuRF1 Protein, active, 10 µg MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: Enzyme Assays
23-054
10 µg  
가격 검색...
가격을 검색할 수 없습니다
Minimum Quantity needs to be mulitiple of
Maximum Quantity is
가격 문의 추가 정보
()이 할인됨
 
—
가격 문의
—
현재 재고 없음 현재 재고 없음
예상 출고 가능일 
단종품
제한된 수량 가능
재고여부 확인
    Remaining: will advise
      Remaining: will advise
      추천사항
      고객 서비스로 문의
      Contact Customer Service

       

      고객 서비스로 문의

      개요

      Replacement Information

      주요 사양표

      Key ApplicationsSpeciesCascade Component
      Enzyme AssaysHuman E3
      Description
      Catalogue Number23-054
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionMuRF1 Protein, active, 10 µg
      Alternate Names
      • E3 ubiquitin-protein ligase TRIM63
      • Iris RING finger protein (IRF)
      • Muscle-specific RING finger protein 1
      • RING finger protein 28 (RNF28)
      • Striated muscle RING zinc finger protein (SMRZ)
      Background InformationMuscle atrophy is a debilitating and life threatening disorder. It is associated with a number of diseases including cancer, diabetes, chronic obstructive pulmonary disease and AIDS and is a natural consequence of inactivity and aging. MuRF1 is an E3 ubiquitin ligase which has been implicated as a component of atrophy-associated proteolysis. It contains an amino terminal RING finger that mediates ubiquitin transfer along with a zinc finger and two coiled-coil domains in its central region. It is up-regulated in a number of different models of atrophy and interacts with numerous myofibrillar proteins as well as Cardiac Troponin I and Creatine Kinase. Deletion of MuRF1 in mice has been shown to inhibit skeletal muscle atrophy suggesting that it may be an important drug target for the prevention of muscle wasting.
      References
      Product Information
      Quality LevelMQ300
      Applications
      ApplicationActive, full length, recombinant human MuRF1. N-terminal GST-tagged. For use in Enzyme Assays. Functions as an E3 ligase in ubiquitination assays.
      Key Applications
      • Enzyme Assays
      Biological Information
      Cascade ComponentE3
      Entrez Gene Number
      Purification MethodPurified using glutathione sepharose.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size10 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      카탈로그 번호 GTIN
      23-054 04053252444104

      관련 제품 및 어플리케이션

      Alternative Packsize

      카탈로그 번호 설명  
      23-054M MuRF1 Protein, active, 250 µg 가격 및 재고 조회

      제품 패밀리

      Ubiquitin Proteasome System: Enzymes and Substrates

      Millipore has removed the complexity of Ubiquitination by providing functionally validated enzymes and substrates, making the pathway readily accessible for research and drug discovery.
      더 보기 >>

      카테고리

      Life Science Research > Drug Discovery and Development > Ubiquitin and Proteasome Screening > Ubiquitin E3 Ligases
      Life Science Research > Proteins and Enzymes > Ubiquitin E3 Ligases