Millipore Sigma Vibrant Logo

444289 Marimastat - CAS 154039-60-8 - Calbiochem

Marimastat, CAS 154039-60-8, is a broad-spectrum MMP inhibitor (IC50 = 5, 6, 200, 20, 2, 1.8 & 3.8 nM for MMP-1, -2, -3, -7, -8, -14 and TACE, respectively).

Marimastat - CAS 154039-60-8 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (2S,3R)-N⁴-((1S)-2,2-Dimethyl-1-((methylamino)carbonyl)propyl)-N¹,2-hydroxy-3-(2-methylpropyl)butanediamide, BB-2516

View Products on Sigmaaldrich.com
444289
가격 및 재고 조회

개요

Replacement Information

주요 사양표

CAS #Empirical Formula
154039-60-8C₁₅H₂₉N₃O₅

가격 및 재고여부

카탈로그 번호 재고 정보패킹 포장 단위 가격(VAT 별도) 수량
444289-5MGCN
재고 정보 검색...
—
현재 재고 없음 현재 재고 없음
예상 출고 가능일 
단종품
제한된 수량 가능
재고여부 확인
    Remaining: will advise
      Remaining: will advise
      추천사항
      고객 서비스로 문의
      Contact Customer Service

      		 Plastic ampoule 5 mg
      가격 검색...
      가격을 검색할 수 없습니다
      Minimum Quantity needs to be mulitiple of
      Maximum Quantity is
      가격 문의 추가 정보
      ()이 할인됨
       
      —
      가격 문의
      		 —
      Description
      OverviewAn orally active peptidyl hydroxamate-based broad-spectrum MMP inhibitor (IC50 in nM = 5, 6, 200, 20, 2, 1.8 and 3.8 for MMP-1, -2, -3, -7, -8, -14 and TACE, respectively) that targets both the substrate binding site and the active-site Zn2+. Marimastate is widely used in studying the involvement of MMPs in various cellular and pathological processes both in vitro and in vivo.
      Catalogue Number444289
      Brand Family Calbiochem®
      Synonyms(2S,3R)-N⁴-((1S)-2,2-Dimethyl-1-((methylamino)carbonyl)propyl)-N¹,2-hydroxy-3-(2-methylpropyl)butanediamide, BB-2516
      References
      ReferencesHansen, H.P., et al. 2002. Int. J. Cancer 98, 210.
      Tsuji, F., et al. 2002. Cytokine 17, 294.
      Barlaam, B., et al. 1999. J. Med. Chem. 42, 4890.
      Whittaker, M., et al. 1999. Chem. Rev. 99, 2735.
      Rasmussen, H.S., and McCann, P.P. 1997. Pharmacol. Ther. 75, 69.
      Product Information
      CAS number154039-60-8
      FormWhite solid
      Hill FormulaC₁₅H₂₉N₃O₅
      Chemical formulaC₁₅H₂₉N₃O₅
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      ApplicationMarimastat, CAS 154039-60-8, is a broad-spectrum MMP inhibitor (IC50 = 5, 6, 200, 20, 2, 1.8 & 3.8 nM for MMP-1, -2, -3, -7, -8, -14 and TACE, respectively).
      Biological Information
      Purity≥98% by NMR
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      S PhraseS: 22-24/25-36/37/39

      Do not breathe dust.
      Avoid contact with skin and eyes.
      Wear suitable protective clothing, gloves and eye/face protection.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      카탈로그 번호 GTIN
      444289-5MGCN 04055977186062

      Documentation

      Marimastat - CAS 154039-60-8 - Calbiochem MSDS

      타이틀

      물질안전보건자료(MSDS) 

      Marimastat - CAS 154039-60-8 - Calbiochem Certificates of Analysis

      TitleLot Number
      444289

      References

      참고문헌 보기
      Hansen, H.P., et al. 2002. Int. J. Cancer 98, 210.
      Tsuji, F., et al. 2002. Cytokine 17, 294.
      Barlaam, B., et al. 1999. J. Med. Chem. 42, 4890.
      Whittaker, M., et al. 1999. Chem. Rev. 99, 2735.
      Rasmussen, H.S., and McCann, P.P. 1997. Pharmacol. Ther. 75, 69.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision25-August-2009 RFH
      Synonyms(2S,3R)-N⁴-((1S)-2,2-Dimethyl-1-((methylamino)carbonyl)propyl)-N¹,2-hydroxy-3-(2-methylpropyl)butanediamide, BB-2516
      DescriptionAn orally active peptidyl hydroxamate-based broad-spectrum MMP inhibitor (IC50 in nM = 5, 6, 200, 20, 2, 1.8 and 3.8 for MMP-1, -2, -3, -7, -8, -14 and TACE, respectively) that targets both the substrate binding site and the active-site Zn2+. Marimastate is widely used in studying the involvement of MMPs in various cellular and pathological processes both in vitro and in vivo.
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number154039-60-8
      Chemical formulaC₁₅H₂₉N₃O₅
      Structure formulaStructure formula
      Purity≥98% by NMR
      SolubilityDMSO (15 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesHansen, H.P., et al. 2002. Int. J. Cancer 98, 210.
      Tsuji, F., et al. 2002. Cytokine 17, 294.
      Barlaam, B., et al. 1999. J. Med. Chem. 42, 4890.
      Whittaker, M., et al. 1999. Chem. Rev. 99, 2735.
      Rasmussen, H.S., and McCann, P.P. 1997. Pharmacol. Ther. 75, 69.