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HGAMMAG-303E

MILLIPLEX® Human Immunoglobulin Isotyping Panel

Human IgE Singleplex Kit

동의어(들):

Human IgE Bead Kit, Human IgE Detection Kit, Immunoglobulin IgE Detection

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12161503
NACRES:
NA.47
eCl@ss:
32161000
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제품 이름

MILLIPLEX® Human Immunoglobulin Isotyping Panel,

Quality Segment

200

description

Human IgE Singleplex Kit

species reactivity

human

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

assay range

accuracy: 102%
(IgE), sensitivity: 0.4 ng/mL, standard curve range: 4.1-1,000 ng/mL
(IgE)

technique(s)

multiplexing: suitable

input

serum
cell culture supernatant(s)
plasma

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

Found only in mammals, Immunoglobulin E (IgE) plays an essential role in allergic reactions and is predominantly associated with type 1 hypersensitivity. IgE is the least abundant immunoglobulin isotype in normal individuals, present at only 0.05% of IgG serum concentrations. It is capable of triggering robust immune reactions, with up to 10 times the typical level detected in the serum of atopic patients, although increased levels occur only in approximately 50% of patients with allergic disorders. IgE binds with high affinity to FcεRI, found primarily on mast cells and basophils, priming the cells to recognize specific antigens such as dust mites, pet dander or pollen. Once primed and with repeated exposure to the same antigen, these cells release molecules such as histamines, prostaglandins, and leukotrienes, resulting in an “allergic reaction”.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Analyze IgE in human serum, plasma, and cell culture supernatants.

Analytes included: IgE

Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

  • Reliable IgE Quantification: Ideal for studying type I hypersensitivity, allergic responses, and atopic conditions, supporting research into asthma, rhinitis, anaphylaxis, and other IgE-mediated disorders.
  • Minimal Sample Volume: Requires only 50 µL of 1:50 diluted serum, plasma, or cell culture supernatant per well.
  • Verified Specificity: No detectable cross-reactivity with other immunoglobulins.
  • Efficient Protocol: One 1-hour and two 30-minute room temperature incubations streamline workflow.

Legal Information

Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

저장 등급

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

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