Millipore Sigma Vibrant Logo

508507 Isradipine - CAS 75695-93-1 - Calbiochem

A voltage gated calcium channel gating inhibitor of the dihydropyridine class.

Isradipine - CAS 75695-93-1 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: L-type voltage-gated Ca2+ channel blocker, Isradipine, PN 200-110

Primary Target: CaV
View Products on Sigmaaldrich.com
508507
가격 및 재고 조회

개요

Replacement Information

주요 사양표

CAS #Empirical Formula
75695-93-1C₁₉H₂₁N₃O₅

가격 및 재고여부

카탈로그 번호 재고 정보패킹 포장 단위 가격(VAT 별도) 수량
5.08507.0001
재고 정보 검색...
—
현재 재고 없음 현재 재고 없음
예상 출고 가능일 
단종품
제한된 수량 가능
재고여부 확인
    Remaining: will advise
      Remaining: will advise
      추천사항
      고객 서비스로 문의
      Contact Customer Service

      		 Glass bottle 10 mg
      가격 검색...
      가격을 검색할 수 없습니다
      Minimum Quantity needs to be mulitiple of
      Maximum Quantity is
      가격 문의 추가 정보
      ()이 할인됨
       
      —
      가격 문의
      		 —
      Description
      OverviewA water soluble voltage gated calcium channel gating inhibitor of the dihydropyridine class. In human ion channels, Isradipine has gating inhibition on Cav1.4 channels (1x10E-6 M) and Cav1.3 (3x10E-8) and in mouse ion channels a pIC50 of 6.7. Often prescribed for hypertension (trade names DynaCirc, Prescal), recent animal models suggest a use in Parkinson′s Disease.

      Please note that the molecular weight for this compound is batch-specific due to variable water content.
      Catalogue Number508507
      Brand Family Calbiochem®
      SynonymsL-type voltage-gated Ca2+ channel blocker, Isradipine, PN 200-110
      References
      ReferencesChan, C. S. et al. 2007. Nature. 447, 1081.
      Baumann, L. et al. 2004. Invest. Ophthalmol. Vis. Sci. 45, 708.
      Koschak, A. et al. 2003. J. Neurosci./i> 23, 6041.
      Koschak, A. et al. 2001. J. Biol Chem 276, 22100.
      Product Information
      CAS number75695-93-1
      FormYellow solid
      Hill FormulaC₁₉H₂₁N₃O₅
      Chemical formulaC₁₉H₂₁N₃O₅
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetCaV
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      카탈로그 번호 GTIN
      5.08507.0001 04055977262001

      Documentation

      Isradipine - CAS 75695-93-1 - Calbiochem MSDS

      타이틀

      물질안전보건자료(MSDS) 

      References

      참고문헌 보기
      Chan, C. S. et al. 2007. Nature. 447, 1081.
      Baumann, L. et al. 2004. Invest. Ophthalmol. Vis. Sci. 45, 708.
      Koschak, A. et al. 2003. J. Neurosci./i> 23, 6041.
      Koschak, A. et al. 2001. J. Biol Chem 276, 22100.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision31-January-2014 JSW
      SynonymsL-type voltage-gated Ca2+ channel blocker, Isradipine, PN 200-110
      DescriptionA water soluble voltage gated calcium channel gating inhibitor of the dihydropyridine class. In human ion channels, Isradipine has gating inhibition on Cav1.4 channels (1x10E-6 M) and Cav1.3 (3x10E-8) and in mouse ion channels a pIC50 of 6.7. Often prescribed for hypertension (trade names DynaCirc, Prescal), recent animal models suggest a use in Parkinson′s Disease.
      FormYellow solid
      CAS number75695-93-1
      Chemical formulaC₁₉H₂₁N₃O₅
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (100 mM) or Ethanol (50 mM)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesChan, C. S. et al. 2007. Nature. 447, 1081.
      Baumann, L. et al. 2004. Invest. Ophthalmol. Vis. Sci. 45, 708.
      Koschak, A. et al. 2003. J. Neurosci./i> 23, 6041.
      Koschak, A. et al. 2001. J. Biol Chem 276, 22100.