Millipore Sigma Vibrant Logo

402088 Indirubin-3ʹ-monoxime-5-sulphonic Acid - CAS 331467-05-1 - Calbiochem

View Products on Sigmaaldrich.com
402088
가격 및 재고 조회

개요

Replacement Information

주요 사양표

CAS #Empirical Formula
331467-05-1C₁₆H₁₁N₃O₅S

가격 및 재고여부

카탈로그 번호 재고 정보패킹 포장 단위 가격(VAT 별도) 수량
402088-1MGCN
재고 정보 검색...
현재 재고 없음
현재 재고 없음
예상 출고 가능일 
단종품
제한된 수량 가능
재고여부 확인
    Remaining: will advise
      Remaining: will advise
      추천사항
      고객 서비스로 문의
      Contact Customer Service

      Plastic ampoule 1 mg
      가격 검색...
      가격을 검색할 수 없습니다
      Minimum Quantity needs to be mulitiple of
      Maximum Quantity is
      가격 문의 추가 정보
      ()이 할인됨
       
      가격 문의
      Description
      OverviewA potent, reversible, and selective inhibitor of Cdk1 (IC50 = 5 nM) and Cdk5 (IC50 = 7 nM) and glycogen synthase kinase-3β (GSK-3β; IC50 = 80 nM). The inhibition is competitive with respect to ATP.
      Catalogue Number402088
      Brand Family Calbiochem®
      References
      ReferencesLeclerc, S., et al. 2001. J. Biol. Chem. 276, 251.
      Product Information
      CAS number331467-05-1
      ATP CompetitiveY
      FormDark red solid
      Hill FormulaC₁₆H₁₁N₃O₅S
      Chemical formulaC₁₆H₁₁N₃O₅S
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetCDK1
      Primary Target IC<sub>50</sub>5 nM, 7 nM, 80 nM, against Cdk1, Cdk5, and glycogen synthase kinase-3β (GSK-3β), respectively
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 4 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      카탈로그 번호 GTIN
      402088-1MGCN 04055977211801

      Documentation

      Indirubin-3ʹ-monoxime-5-sulphonic Acid - CAS 331467-05-1 - Calbiochem MSDS

      타이틀

      물질안전보건자료(MSDS) 

      Indirubin-3ʹ-monoxime-5-sulphonic Acid - CAS 331467-05-1 - Calbiochem Certificates of Analysis

      TitleLot Number
      402088

      References

      참고문헌 보기
      Leclerc, S., et al. 2001. J. Biol. Chem. 276, 251.

      Brochure

      Title
      Alzheimer's Disease Brochure & Technical Guide
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-April-2011 RFH
      DescriptionA highly potent, reversible, and selective inhibitor of cyclin-dependent kinases 1 and 5 (IC50 = 5 nM for CDK1; IC50 = 7 nM for CDK5). Reported to act by competing with ATP for binding to the catalytic site of the kinase. Also acts as a potent inhibitor of glycogen synthase kinase-3β (GSK-3β; IC50 = 80 nM).
      FormDark red solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number331467-05-1
      Chemical formulaC₁₆H₁₁N₃O₅S
      Structure formulaStructure formula
      Purity≥97% by HPLC
      SolubilityDMSO (50 mg/ml)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 4 months at -20°C.
      Toxicity Standard Handling
      ReferencesLeclerc, S., et al. 2001. J. Biol. Chem. 276, 251.