SCC069
HSC-T6 Rat Hepatic Stellate Cell Line
Rat
동의어(들):
HSC, Perisinusoidal cells, Ito cells, Hepatic lipocytes, Hepatic pericytes
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
제품정보 (DICE 배송 시 비용 별도)
UNSPSC Code:
41106514
NACRES:
NA.81
eCl@ss:
32011203
Biological source:
rat
제품 이름
HSC-T6 Rat Hepatic Stellate Cell Line, The HSC-T6 rat hepatic stellate cell line is a valuable cell model for studies of retinoid metabolism based on their similar retinoid phenotype as primary cells.
biological source
rat
technique(s)
cell based assay: suitable, cell culture | mammalian: suitable
shipped in
ambient
Quality Level
General description
Hepatocytes and hepatic stellate cells play important roles in retinoid uptake, storage, mobilization and metabolism. Hepatic stellate cells represent only 5-7% of the total cells present in the liver. Isolation of primary stellate cells is thus time-consuming and often accompanied by low yields and considerable lot-to-lot variations. HSC-T6 Rat Hepatic Stellate Cell Line is an immortalized line isolated from SV40 large T-antigen transformed primary stellate cells of male Sprague-Dawley retired breeder rats. HSC-T6 Rat Hepatic Stellate Cell line is a useful model for the study of hepatic retinoid storage and metabolism.
Application
Research Category
Metabolism
Infectious Diseases
Inflammation & Immunology
Stem Cell Research
Metabolism
Infectious Diseases
Inflammation & Immunology
Stem Cell Research
Research Sub Category
Liver Physiology
Liver Physiology
Subject to local law, this product is intended to be sold for internal in vitro research use only subject to terms and conditions found here: www.sigmaaldrich.com/restrictedcelluse. This product may not be: re-engineered or copied; used to make derivatives, modifications or functional equivalents; used to obtain patents or other IP claiming use of the product; used to develop, test, or manufacturer a commercial product; used as a component in a commercial product; resold or licensed; used in any clinical applications or trials; or used in humans. A license or limited commercial use agreement is required for use by any for-profit entity, use in services, and use in sponsored academic research. For information regarding any such use, please contact licensing@milliporesigma.com.
Biochem/physiol Actions
Hepatocyte Cells
Preparation Note
HSC-T6 Rat Hepatic Stellate Cells should be stored in liquid nitrogen. The cells can be cultured for at least 10 passages after initial thawing without significantly affecting the cell marker expression and functionality.
Analysis Note
• Each vial contains ≥ 1X106 viable cells.
• Cells tested negative for infectious diseases by a Mouse/Rat Comprehensive CLEAR panel PCR panel by Charles River Animal Diagnostic Services.
• Cells tested negative for mycoplasma contamination.
• Cells tested negative for infectious diseases by a Mouse/Rat Comprehensive CLEAR panel PCR panel by Charles River Animal Diagnostic Services.
• Cells tested negative for mycoplasma contamination.
Other Notes
1) ≥1X106 viable HSC-T6 Rat Hepatic Stellate Cells: (Catalog No. SCC069). Store in liquid nitrogen.
저장 등급
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Ryuichi Noguchi et al.
Molecular medicine reports, 22(4), 2948-2956 (2020-09-19)
An orally bioavailable small molecule inhibitor of plasminogen activator inhibitor‑1 (PAI‑1) is currently being clinically assessed as a novel antithrombotic agent. Although PAI‑1 is known to serve a key role in the pathogenesis of metabolic syndrome (MetS) including nonalcoholic steatohepatitis
Scott L Friedman et al.
Methods in molecular biology (Clifton, N.J.), 2669, 129-162 (2023-05-29)
Hepatic stellate cells (HSCs) are the major cellular source of extracellular matrix production in the liver. Therefore, this cell population has received considerable attention in studies investigating fundamental features of hepatic fibrosis. However, the limited supply and ever-increasing demand for
Hsiao-Hsuan Wang et al.
EBioMedicine, 64, 103213-103213 (2021-01-29)
Interleukin-24 (IL-24) binds to two kinds of receptor complexes, namely IL-20R1/IL-20R2 and IL-20R2/IL-22R1, which are also bound by IL-20. IL-20 plays a detrimental role in liver fibrosis. Due to the sharing of receptor complexes, we aimed to determine whether IL-24
Jiunn-Sheng Wu et al.
Evidence-based complementary and alternative medicine : eCAM, 2020, 8426051-8426051 (2020-07-28)
Hepatic stellate cell (HSC) activation is a vital driver of liver fibrosis. Recent research efforts have emphasized the clearance of activated HSCs by apoptosis, senescence, or reversion to the quiescent state. LPS induces human HSC activation directly and contributes to
Hongxia Liang et al.
ACS nano, 12(7), 6536-6544 (2018-06-27)
Acute liver failure is a critical condition characterized by global hepatocyte death and often time needs a liver transplantation. Such treatment is largely limited by donor organ shortage. Stem cell therapy offers a promising option to patients with acute liver
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| SCC069 | 04054839083891 |
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