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343020 Flt-3 Inhibitor - CAS 301305-73-7 - Calbiochem

The Flt-3 Inhibitor, also referenced under CAS 301305-73-7, controls the biological activity of Flt-3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: Flt-3
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343020
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개요

Replacement Information

주요 사양표

CAS #Empirical Formula
301305-73-7C₁₈H₂₀N₂O₄S

가격 및 재고여부

카탈로그 번호 재고 정보패킹 포장 단위 가격(VAT 별도) 수량
343020-5MGCN
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      		 Plastic ampoule 5 mg
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      Description
      OverviewA cell-permeable thienylcarboxamide compound that acts as a potent, ATP-competitive, and highly selective Flt-3 inhibitor (IC50 = 42 nM) with little effect against a panel of 22 other kinases (IC50 ≥3 µM). Shown to exhibit antiproliferative properties against the human acute myelogenous leukemia cell line MV4-11 (IC50 = 340 nM) expressing constitutively active Flt-3.
      Catalogue Number343020
      Brand Family Calbiochem®
      References
      ReferencesPatch, R.J., et al. 2006. Bioorg. Med. Chem. Lett. 16, 3282.
      Product Information
      CAS number301305-73-7
      ATP CompetitiveY
      FormWhite solid
      Hill FormulaC₁₈H₂₀N₂O₄S
      Chemical formulaC₁₈H₂₀N₂O₄S
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetFlt-3
      Primary Target IC<sub>50</sub>42 nM against Flt-3
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      카탈로그 번호 GTIN
      343020-5MGCN 04055977195019

      Documentation

      Flt-3 Inhibitor - CAS 301305-73-7 - Calbiochem MSDS

      타이틀

      물질안전보건자료(MSDS) 

      Flt-3 Inhibitor - CAS 301305-73-7 - Calbiochem Certificates of Analysis

      TitleLot Number
      343020

      References

      참고문헌 보기
      Patch, R.J., et al. 2006. Bioorg. Med. Chem. Lett. 16, 3282.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision10-October-2007 JSW
      DescriptionA cell-permeable thienylcarboxamide compound that acts as a potent, ATP-competitive, and highly selective Flt-3 inhibitor (IC50 = 42 nM) with little effect against a panel of 22 other kinases (IC50 ≥3 µM). Shown to exhibit antiproliferative properties against the human acute myelogenous leukemia cell line MV4-11 (IC50 = 340 nM) expressing constitutively active Flt-3.
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number301305-73-7
      Chemical formulaC₁₈H₂₀N₂O₄S
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (<4 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Irritant
      ReferencesPatch, R.J., et al. 2006. Bioorg. Med. Chem. Lett. 16, 3282.