Millipore Sigma Vibrant Logo

371208 Dkk-1, Rat, Recombinant

Dkk-1, Rat, Recombinant, consists of amino acids 23-270, fused at the C-terminus to a His•Tag® sequence, and expressed in NS0-derived mouse myeloma cells.

Dkk-1, Rat, Recombinant MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
View Products on Sigmaaldrich.com
371208
가격 및 재고 조회

개요

Replacement Information

주요 사양표

Purity
≥95% by SDS-PAGE

가격 및 재고여부

카탈로그 번호 재고 정보패킹 포장 단위 가격(VAT 별도) 수량
371208-10UGCN
재고 정보 검색...
—
현재 재고 없음 현재 재고 없음
예상 출고 가능일 
단종품
제한된 수량 가능
재고여부 확인
    Remaining: will advise
      Remaining: will advise
      추천사항
      고객 서비스로 문의
      Contact Customer Service

      		 Glass bottle 10 μg
      가격 검색...
      가격을 검색할 수 없습니다
      Minimum Quantity needs to be mulitiple of
      Maximum Quantity is
      가격 문의 추가 정보
      ()이 할인됨
       
      —
      가격 문의
      		 —
      Description
      OverviewRecombinant, rat Dickkopf related protein-1 (Dkk-1), consisting of amino acids 23-270, fused at the C-terminus to a His•Tag® sequence, and expressed in NS0-derived mouse myeloma cells. The balance between Wnt signaling and Dkk-1 inhibition is essential for bone formation and homeostasis.
      Catalogue Number371208
      Brand Family Calbiochem®
      References
      ReferencesLi, J. et al. 2006. Bone 36, 754.
      Morvan, F. et al. 2006. J. Bone Miner. Res. 21, 934.
      Niehrs, C. 2006. Oncogene 25, 7469.
      Verani, R. et al. 2006. J. Neurochem. 101, 242.
      Cappuccio, I. et al. 2005. J. Neurosci. 25, 2647.
      Kemp, C. et al. 2005. Dev. Dyn. 233, 1064.
      Adamska, M. et al. 2004. Dev. Biol. 272, 134.
      Bullock, C.M. et al. 2004. Mol. Pharmacol. 65, 582.
      Mao, B. et al. 2002. Nature 417, 664.
      Mao, B. et al. 2001. Nature 411, 321.
      Krupnik, V.E., et al. 1999. Gene 238, 301.
      Product Information
      FormLyophilized
      FormulationLyophilized from 0.2 µm filtered PBS, BSA.
      Quality LevelMQ100
      Applications
      Biological Information
      Biological activityND₅₀ = 0.1-0.5 µg/ml as measured by inhibition of Wnt-3a-induced (10 ng/ml rmWnt-3a) alkaline phosphatase production by proliferation of MC3T3-E1 mouse osteoblastic cells.
      Purity≥95% by SDS-PAGE
      Physicochemical Information
      ContaminantsEndotoxin: ≤1.0 EU/µg protein
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      카탈로그 번호 GTIN
      371208-10UGCN 04055977213829

      Documentation

      Dkk-1, Rat, Recombinant MSDS

      타이틀

      물질안전보건자료(MSDS) 

      Dkk-1, Rat, Recombinant Certificates of Analysis

      TitleLot Number
      371208

      References

      참고문헌 보기
      Li, J. et al. 2006. Bone 36, 754.
      Morvan, F. et al. 2006. J. Bone Miner. Res. 21, 934.
      Niehrs, C. 2006. Oncogene 25, 7469.
      Verani, R. et al. 2006. J. Neurochem. 101, 242.
      Cappuccio, I. et al. 2005. J. Neurosci. 25, 2647.
      Kemp, C. et al. 2005. Dev. Dyn. 233, 1064.
      Adamska, M. et al. 2004. Dev. Biol. 272, 134.
      Bullock, C.M. et al. 2004. Mol. Pharmacol. 65, 582.
      Mao, B. et al. 2002. Nature 417, 664.
      Mao, B. et al. 2001. Nature 411, 321.
      Krupnik, V.E., et al. 1999. Gene 238, 301.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision22-June-2011 RFH
      DescriptionRecombinant, rat Dickkopf related protein-1 (Dkk-1), consisting of amino acids 23-270, fused at the C-terminus to a His•Tag® sequence, and expressed in NS0-derived mouse myeloma cells. The balance between Wnt signaling and Dkk-1 inhibition is essential for bone formation and homeostasis.
      FormLyophilized
      FormulationLyophilized from 0.2 µm filtered PBS, BSA.
      Purity≥95% by SDS-PAGE
      ContaminantsEndotoxin: ≤1.0 EU/µg protein
      Biological activityND₅₀ = 0.1-0.5 µg/ml as measured by inhibition of Wnt-3a-induced (10 ng/ml rmWnt-3a) alkaline phosphatase production by proliferation of MC3T3-E1 mouse osteoblastic cells.
      SolubilityReconstitute to 100 µg/ml with sterile PBS containing ≥1% human or bovine serum albumin.
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesLi, J. et al. 2006. Bone 36, 754.
      Morvan, F. et al. 2006. J. Bone Miner. Res. 21, 934.
      Niehrs, C. 2006. Oncogene 25, 7469.
      Verani, R. et al. 2006. J. Neurochem. 101, 242.
      Cappuccio, I. et al. 2005. J. Neurosci. 25, 2647.
      Kemp, C. et al. 2005. Dev. Dyn. 233, 1064.
      Adamska, M. et al. 2004. Dev. Biol. 272, 134.
      Bullock, C.M. et al. 2004. Mol. Pharmacol. 65, 582.
      Mao, B. et al. 2002. Nature 417, 664.
      Mao, B. et al. 2001. Nature 411, 321.
      Krupnik, V.E., et al. 1999. Gene 238, 301.