Millipore Sigma Vibrant Logo

219433 Cathepsin L Inhibitor IV - Calbiochem

View Products on Sigmaaldrich.com
219433
가격 및 재고 조회

개요

Replacement Information

주요 사양표

Empirical Formula
C₂₇H₂₉N₃O₄S

가격 및 재고여부

카탈로그 번호 재고 정보패킹 포장 단위 가격(VAT 별도) 수량
219433-1MGCN
재고 정보 검색...
현재 재고 없음
현재 재고 없음
예상 출고 가능일 
단종품
제한된 수량 가능
재고여부 확인
    Remaining: will advise
      Remaining: will advise
      추천사항
      고객 서비스로 문의
      Contact Customer Service

      Plastic ampoule 1 mg
      가격 검색...
      가격을 검색할 수 없습니다
      Minimum Quantity needs to be mulitiple of
      Maximum Quantity is
      가격 문의 추가 정보
      ()이 할인됨
       
      가격 문의
      Description
      OverviewA potent, cell-permeable, selective, and reversible inhibitor of cathepsin L (IC50 = 1.9 nM). Also inhibits the release of Ca2+ and hydroxyproline from bone in an in vitro bone culture system and prevents bone loss in ovariectomized mice (~50 mg/kg).
      Catalogue Number219433
      Brand Family Calbiochem®
      Synonyms1-Naphthalenesulfonyl-IW-CHO
      References
      ReferencesYasuma, T., et al. 1998. J. Med. Chem. 41, 4301.
      Product Information
      ATP CompetitiveN
      FormWhite to off-white solid
      Hill FormulaC₂₇H₂₉N₃O₄S
      Chemical formulaC₂₇H₂₉N₃O₄S
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetcathepsin L
      Primary Target IC<sub>50</sub>1.9 nM against Cathepsin L
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableY
      Peptide Sequence1-Naphthalenesulfonyl-Ile-Trp-CHO
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      카탈로그 번호 GTIN
      219433-1MGCN 04055977218381

      Documentation

      Cathepsin L Inhibitor IV - Calbiochem MSDS

      타이틀

      물질안전보건자료(MSDS) 

      Cathepsin L Inhibitor IV - Calbiochem Certificates of Analysis

      TitleLot Number
      219433

      References

      참고문헌 보기
      Yasuma, T., et al. 1998. J. Med. Chem. 41, 4301.

      Citations

      타이틀
    • Moin U Fareed, et al. (2006) Treatment of rats with calpain inhibitors prevents sepsis-induced muscle proteolysis independent of atrogin-1/MAFbx and MuRF1 expression. American Journal of Physiology Regulatory, Integrative and Comparative Physiology 290, R1589-R1597.
    • Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision03-January-2019 JSW
      Synonyms1-Naphthalenesulfonyl-IW-CHO
      DescriptionA potent, cell-permeable, selective, and reversible inhibitor of cathepsin L (IC50 = 1.9 nM). Inhibits the release of Ca2+ and hydroxyproline from bone in a bone culture system and prevents bone loss in ovariectomized mice (~50 mg/kg).
      FormWhite to off-white solid
      Chemical formulaC₂₇H₂₉N₃O₄S
      Peptide Sequence1-Naphthalenesulfonyl-Ile-Trp-CHO
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (5 mg/ml)
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesYasuma, T., et al. 1998. J. Med. Chem. 41, 4301.
      Citation
    • Moin U Fareed, et al. (2006) Treatment of rats with calpain inhibitors prevents sepsis-induced muscle proteolysis independent of atrogin-1/MAFbx and MuRF1 expression. American Journal of Physiology Regulatory, Integrative and Comparative Physiology 290, R1589-R1597.