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205546 Caffeic Acid - CAS 331-39-5 - Calbiochem

A natural dietary compound reported to have anti-carcinogenic and anti-inflammatory properties.

Caffeic Acid - CAS 331-39-5 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 3,4-Dihydroxycinnamic Acid

Primary Target: 5-lipoxygenase
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205546
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개요

Replacement Information

주요 사양표

CAS #Empirical Formula
331-39-5C₉H₈O₄

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205546-500MGCN
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      		 Plastic ampoule 500 mg
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      Description
      OverviewA natural dietary compound reported to have anti-carcinogenic and anti-inflammatory properties. A cell-permeable, selective, non-competitive inhibitor of 5-lipoxygenase (ID50 = 3.7 µM). Inhibits Cu2+-induced LDL oxidation in the initiation phase but acts as a prooxidant in the propagation phase. An irreversible inhibitor of glutathione S-transferases and a non-competitive inhibitor of xanthine oxidase.
      Catalogue Number205546
      Brand Family Calbiochem®
      Synonyms3,4-Dihydroxycinnamic Acid
      References
      ReferencesYamanaka, N., et al. 1997. FEBS Lett. 405, 186.
      Chan, W.S., et al. 1995. Anticancer Res. 15, 703.
      Ploemen, J.H., et al. 1993. Food Chem. Toxicol. 31, 475.
      Koshihara, Y., et al. 1984. Biochim. Biophys. Acta 792, 92.
      Product Information
      CAS number331-39-5
      ATP CompetitiveN
      FormTan crystalline solid
      Hill FormulaC₉H₈O₄
      Chemical formulaC₉H₈O₄
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Target5-lipoxygenase
      Primary Target IC<sub>50</sub>3.7 µM against 5-lipoxygenase
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSGD8950000
      Safety Information
      R PhraseR: 40

      Limited evidence of a carcinogenic effect.
      S PhraseS: 36/37

      Wear suitable protective clothing and gloves.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Carcinogenic / Teratogenic
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      카탈로그 번호 GTIN
      205546-500MGCN 04055977203134

      Documentation

      Caffeic Acid - CAS 331-39-5 - Calbiochem MSDS

      타이틀

      물질안전보건자료(MSDS) 

      Caffeic Acid - CAS 331-39-5 - Calbiochem Certificates of Analysis

      TitleLot Number
      205546

      References

      참고문헌 보기
      Yamanaka, N., et al. 1997. FEBS Lett. 405, 186.
      Chan, W.S., et al. 1995. Anticancer Res. 15, 703.
      Ploemen, J.H., et al. 1993. Food Chem. Toxicol. 31, 475.
      Koshihara, Y., et al. 1984. Biochim. Biophys. Acta 792, 92.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision28-April-2008 RFH
      Synonyms3,4-Dihydroxycinnamic Acid
      DescriptionA cell-permeable natural dietary compound reported to have anti-carcinogenic and anti-inflammatory properties. A selective, non-competitive inhibitor of 5-lipoxygenase (ID50 = 3.7 µM). Inhibits Cu2+-induced LDL oxidation in the initiation phase but acts as a prooxidant in the propagation phase. An effective irreversible inhibitor of glutathione S-transferases and a non-competitive inhibitor of xanthine oxidase.
      FormTan crystalline solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number331-39-5
      RTECSGD8950000
      Chemical formulaC₉H₈O₄
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMSO (200 mg/ml) or Ethanol (50 mg/ml)
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Carcinogenic / Teratogenic
      Merck USA index14, 1635
      ReferencesYamanaka, N., et al. 1997. FEBS Lett. 405, 186.
      Chan, W.S., et al. 1995. Anticancer Res. 15, 703.
      Ploemen, J.H., et al. 1993. Food Chem. Toxicol. 31, 475.
      Koshihara, Y., et al. 1984. Biochim. Biophys. Acta 792, 92.