Millipore Sigma Vibrant Logo

203811 Bryostatin 1 - CAS 83314-01-6 - Calbiochem

View Products on Sigmaaldrich.com
203811
가격 및 재고 조회

개요

주요 사양표

CAS #Empirical Formula
83314-01-6C₄₇H₆₈O₁₇

가격 및 재고여부

카탈로그 번호 재고 정보패킹 포장 단위 가격(VAT 별도) 수량
203811-10UGCN
현재 재고 없음
현재 재고 없음
예상 출고 가능일 
단종품
제한된 수량 가능
재고여부 확인
    Remaining: will advise
      Remaining: will advise
      추천사항
      고객 서비스로 문의
      Contact Customer Service

      Plastic ampoule 10 μg
      가격을 검색할 수 없습니다
      Minimum Quantity needs to be mulitiple of
      Maximum Quantity is
      가격 문의 추가 정보
      ()이 할인됨
       
      가격 문의
      Description
      OverviewA macrocyclic lactone with antitumor properties. Potently activates protein kinase C and exhibits a high binding affinity (Ki = 1.35 nM). Effectively translocates and down-regulates PKC isozymes α, δ, and ε. Induces a biphasic activation of PKD through a PKC-dependent pathway in intact cells. Also shown to activate Ras in Jurkat T cells and in rat2 cells.
      Catalogue Number203811
      Brand Family Calbiochem®
      SynonymsBryo 1, PKC Activator VII, PKC Activator VI
      References
      ReferencesClamp, A., and Jayson, G. 2002. Anticancer Drugs 13, 673.
      Lorenzo, P.S., et al. 1999. Cancer Res. 59, 6137.
      Wang, Q.J., et al. 1999. J. Biol. Chem. 274, 37233.
      Wender, P.A., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 6624.
      Matthews, S.A., et al. 1997. J. Biol. Chem. 272, 20245.
      Szallasi, Z., et al. 1994. Mol. Pharmacol. 46, 840.
      Berkow, R.L., and Kratt, A.S. 1985. Biochem. Biophys. Res. Commun. 3, 1109.
      Product Information
      CAS number83314-01-6
      ATP CompetitiveN
      FormWhite to colorless solid or film
      Hill FormulaC₄₇H₆₈O₁₇
      Chemical formulaC₄₇H₆₈O₁₇
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary TargetProtein kinase C
      Primary Target K<sub>i</sub>1.35 nM for protein kinase C
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableN
      Safety Information according to GHS
      RTECSEH9455000
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Global Trade Item Number
      카탈로그 번호 GTIN
      203811-10UGCN 04055977204025