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PF126 Bcl-2, C-Terminal Truncated, His•Tag®, Human, Recombinant, E. coli

Recombinant, human Bcl-2 without the 17 amino acid mitochondrial targeting sequence at the C-terminus, fused to a His•Tag® sequence, and expressed in E. coli.

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PF126
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PF126-50UGCN
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      		 Glass bottle 50 μg
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      Description
      OverviewRecombinant, human Bcl-2 without the 17 amino acid mitochondrial targeting sequence at the C-terminus, fused to a His•Tag® sequence, and expressed in E. coli. The truncated protein retains the ability to neutralize pro-apoptotic Bcl-2 family members.
      Catalogue NumberPF126
      Brand Family Calbiochem®
      Product Information
      FormLiquid
      FormulationIn 100 mM KCl, 10 mM HEPES, 20% glycerol, pH 8.0.
      Quality LevelMQ100
      Applications
      Key Applications
      Application NotesNeutralization (see biological activity)
      Biological Information
      Biological activityEC₅₀ = 100-300 nM based on its ability to inhibit 54 nM caspase-8-cleaved human Bid-mediated release of cytochrome c from isolated mouse liver mitochondria
      Purity≥95% by SDS-PAGE
      Species Reactivity
      • Human
      Concentration Label Please refer to vial label for lot-specific concentration
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Global Trade Item Number
      카탈로그 번호 GTIN
      PF126-50UGCN 04055977226904