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182540 Aromatase Inhibitor I - CAS 331684-05-0 - Calbiochem

The Aromatase Inhibitor I, also referenced under CAS 331684-05-0, controls the biological activity of Aromatase.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 4-(Imidazolylmethyl)-1-nitro-9H-9-xanthenone

Primary Target: P450 arom.
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182540
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개요

Replacement Information

주요 사양표

CAS #Empirical Formula
331684-05-0C₁₇H₁₁N₃O₄

가격 및 재고여부

카탈로그 번호 재고 정보패킹 포장 단위 가격(VAT 별도) 수량
182540-1MGCN
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      		 Plastic ampoule 1 mg
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      Description
      OverviewA potent, competitive, nonsteroidal inhibitor of aromatase (P450arom; IC50 = 40 nM for human aromatase). Reported to be more potent than fadrozole in inhibiting aromatase activity. Does not significantly inhibit 17α-hydroxylase.
      Catalogue Number182540
      Brand Family Calbiochem®
      Synonyms4-(Imidazolylmethyl)-1-nitro-9H-9-xanthenone
      References
      ReferencesRecanatini, M., et al. 2001. J. Med. Chem. 44, 672.
      Product Information
      CAS number331684-05-0
      ATP CompetitiveY
      FormWhite solid
      Hill FormulaC₁₇H₁₁N₃O₄
      Chemical formulaC₁₇H₁₁N₃O₄
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetP450 arom.
      Primary Target IC<sub>50</sub>40 nM against P450arom
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      카탈로그 번호 GTIN
      182540-1MGCN 04055977205091

      Documentation

      Aromatase Inhibitor I - CAS 331684-05-0 - Calbiochem MSDS

      타이틀

      물질안전보건자료(MSDS) 

      Aromatase Inhibitor I - CAS 331684-05-0 - Calbiochem Certificates of Analysis

      TitleLot Number
      182540

      References

      참고문헌 보기
      Recanatini, M., et al. 2001. J. Med. Chem. 44, 672.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision05-April-2011 RFH
      Synonyms4-(Imidazolylmethyl)-1-nitro-9H-9-xanthenone
      DescriptionA potent, selective, nonsteroidal, competitive inhibitor of aromatase (P450arom) (IC50 = 40 nM for human aromatase) Reported to be more potent than fadrozole in inhibiting aromatase activity. Does not significantly inhibit human 17α-hydroxylase (P450 17) (4% inhibition at 2.5 µM).
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number331684-05-0
      Chemical formulaC₁₇H₁₁N₃O₄
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMSO (25 mg/ml)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesRecanatini, M., et al. 2001. J. Med. Chem. 44, 672.