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178223 Antipain, Dihydrochloride - CAS 37682-72-7 - Calbiochem

Peptidyl arginine aldehyde protease inhibitor produced by actinomycetes.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: trypsin-like serine proteases, papain, and some cysteine proteases
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178223
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개요

주요 사양표

CAS #Empirical Formula
37682-72-7C₂₇H₄₄N₁₀O₆ · 2HCl

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178223-10MGCN
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      		 Plastic ampoule 10 mg
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      Description
      OverviewPeptidyl arginine aldehyde protease inhibitor produced by actinomycetes. Inhibitor of Ca2+-dependent endopeptidases. Has specificity similar to Leupeptin (Cat. No. 108975). Inhibits trypsin-like serine proteases, papain and some cysteine proteases (IC50 = 300 µM).
      Effective concentration: 1-100 µM.
      Catalogue Number178223
      Brand Family Calbiochem®
      References
      ReferencesLyupina, Y.V., et al. 1996. Eur. J. Pharmacol. 304, 23.
      Ichikawa, S., et al. 1985. J. Reprod. Fertil. 73, 385
      Umezawa, H. 1976. Methods Enzymol. 55, 678.
      Suda, H., et al. 1972. J. Antibiot. (Tokyo) 25, 263.
      Product Information
      CAS number37682-72-7
      ATP CompetitiveN
      FormWhite powder
      Hill FormulaC₂₇H₄₄N₁₀O₆ · 2HCl
      Chemical formulaC₂₇H₄₄N₁₀O₆ · 2HCl
      Hygroscopic Hygroscopic
      ReversibleY
      Quality LevelMQ100
      Biological Information
      Primary Targettrypsin-like serine proteases, papain, and some cysteine proteases
      Primary Target IC<sub>50</sub>300 µM against trypsin-like serine proteases, papain and some cysteine proteases; Effective concentration: 1-100 µM
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableN
      Safety Information according to GHS
      RTECSYV9350800
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 1 week at 4°C or for up to 1 month at -20°C.
      Global Trade Item Number
      카탈로그 번호 GTIN
      178223-10MGCN 04055977223118