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ABE284 Anti-T-box transcription factor TBX5 Antibody

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ABE284
100 µL  
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      개요

      Replacement Information

      주요 사양표

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RWB, ICC, IHCRbSerumPolyclonal Antibody
      Description
      Catalogue NumberABE284
      DescriptionAnti-T-box transcription factor TBX5 Antibody
      Alternate Names
      • T-box transcription factor TBX5
      • T-box protein 5
      Background InformationThe gene encoding T-box transcription factor 5 (TBX5) is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity.
      References
      Product Information
      FormatSerum
      Control
      • HeLa cell lysate
      PresentationRabbit polyclonal serum with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-T-box transcription factor TBX5 Antibody detects level of T-box transcription factor TBX5 & has been published & validated for use in Western Blotting, ICC & IHC.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      • Immunohistochemistry
      Application NotesImmunocytochemistry Analysis: A representative lot from an independent laboratory detected T-box transcription factor TBX5 in 293T cells overexpressing T-box transcription factor TBX5, mouse primary cardiocytes treated with serum, HA-tagged Tbx5 transfected NIH/3T3 cells, and HA-tagged Tbx5 transfected C2C12 cells (Georges, R., et al. (2008). Mol Cell Biol. 28(12):4052-4067.)

      Immunohistochemistry Analysis: A representative lot from an independent laboratory detected T-box transcription factor TBX5 in mouse embryonic tissue and in Tbx5 transgenic mouse heart tissues treated with tamoxifin (Georges, R., et al. (2008). Mol Cell Biol. 28(12):4052-4067.).
      Biological Information
      ImmunogenRecombinant protein corresponding to mouse T-box transcription factor TBX5.
      HostRabbit
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • Tbx5
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~53 kDa observed. An uncharacterized band may be observed at ~75 kDa in some cell lysates. Three isoforms due to alternative splicing may be observed at ~35 kDa, ~50 kDa, and ~64 kDa in some cell lysates. (Georges, R., et al. (2008). Mol Cell Biol. 28(12):4052-4067.).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in HeLa cell lysate.

      Western Blot Analysis: A 1:1,000 dilution from a representative lot detected T-box transcription factor TBX5 in 10 µg of HeLa cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      카탈로그 번호 GTIN
      ABE284 04053252819018

      Documentation

      Anti-T-box transcription factor TBX5 Antibody MSDS

      타이틀

      물질안전보건자료(MSDS) 

      Anti-T-box transcription factor TBX5 Antibody Certificates of Analysis

      TitleLot Number
      Anti-T-box transcription factor TBX5 - 2460985 2460985
      Anti-T-box transcription factor TBX5 - 2535306 2535306
      Anti-T-box transcription factor TBX5 - 2843850 2843850
      Anti-T-box transcription factor TBX5 - Q2064901 Q2064901
      Anti-T-box transcription factor TBX5 -2490009 2490009
      Anti-T-box transcription factor TBX5 -2679483 2679483
      Anti-T-box transcription factor TBX5 -2849045 2849045
      Anti-T-box transcription factor TBX5 -2887443 2887443
      Anti-T-box transcription factor TBX5 Polyclonal Antibody 3060087
      Anti-T-box transcription factor TBX5 Polyclonal Antibody 2874613

      References

      Reference overviewPub Med ID
      Distinct expression and function of alternatively spliced Tbx5 isoforms in cell growth and differentiation.
      Georges, R; Nemer, G; Morin, M; Lefebvre, C; Nemer, M
      Molecular and cellular biology  28  4052-67  2008

      요약 표시 기사 전문
      18391012 18391012

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      카테고리

      Life Science Research > Antibodies and Assays > Primary Antibodies