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ABC846 Anti-Slc22A17 Antibody

Anti-Slc22A17 Antibody is an antibody against Slc22A17 for use in western blotting & immunofluorescence.

Anti-Slc22A17 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: SLC22A17, BOCT, BOIT UniProt Number: Q8WUG5
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ABC846
100 µg  
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      주요 사양표

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IFRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABC846
      DescriptionAnti-Slc22A17 Antibody
      Alternate Names
      • Solute carrier family 22 member 17
      • 24p3 receptor
      • 24p3R
      • Brain-type organic cation transporter
      • Lipocalin-2 receptor
      • Neutrophil gelatinase-associated lipocalin receptor
      • NgalR
      • Slc22A17
      Background InformationSolute carrier family 22 member 17, also known as 24p3 receptor (24p3R) or Brain-type organic cation transporter or Lipocalin-2 receptor or Neutrophil gelatinase-associated lipocalin receptor (NgalR), and encoded by the gene name SLC22A17 or BOCT or BOIT, is a family of organic anion and cation transporters (OATs, OCTs, OCTNs) that are expressed in brain. Each contain 12 predicted alpha-helical transmembrane domains (TMDs) and one large extracellular loop between TMDs 1 and 2. Transporters of the SLC22 family function in different ways such as uniporters that mediate facilitated diffusion in either direction (OCTs), as anion exchangers (OAT1, OAT3 and URAT1), and as Na(+)/l-carnitine cotransporter (OCTN2). Slc22 family members participate in the absorption and/or excretion of drugs, xenobiotics, and endogenous compounds in intestine, liver, and kidney, and perform homeostatic functions in brain and heart. Mutations in the Slc22 family may cause specific diseases such as primary systemic carnitine deficiency or idiopathic renal hypouricemia and may change drug absorption or excretion. Recent studies show the expression of Slc22A17 as receptor for Lipocalin 2 is relatively high in hematopoietic stem cells.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Slc22A17 Antibody is an antibody against Slc22A17 for use in western blotting & immunofluorescence.
      Key Applications
      • Western Blotting
      • Immunofluorescence
      Application NotesImmunofluorescence Analysis: 20 μg/mL from a representative lot detected Slc22A17 in rat kidney tissue.
      Biological Information
      ImmunogenKLH-conjugated synthetic peptide corresponding to the C-terminus of human Slc22A17.
      EpitopeC-terminus
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • SLC22A17
      • BOCT
      • BOIT
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~60 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in SK-N-SH cell lysate with and without blocking peptide.

      Western Blotting Analysis: 1 μg/mL of this antibody detected Slc22A17 in SK-N-SH cell lysate with and without blocking peptide.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      카탈로그 번호 GTIN
      ABC846 04053252943966