MAB5352
Anti-Notch 1 Antibody, clone mN1A
clone mN1A, Chemicon®, from mouse
동의어(들):
Anti-AOS5, Anti-AOVD1, Anti-TAN1, Anti-hN1
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크기 선택
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제품정보 (DICE 배송 시 비용 별도)
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
mN1A, monoclonal
Application:
ICC, IHC, IP, WB
Citations:
12
biological source
mouse
Quality Segment
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
mN1A, monoclonal
species reactivity
rat, mouse, feline
packaging
antibody small pack of 25 μg
manufacturer/tradename
Chemicon®
technique(s)
immunocytochemistry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
ambient
storage temp.
2-8°C
target post-translational modification
unmodified
Gene Information
human ... NOTCH1(4851)
General description
272.5 kDa (also 230 kDa processed form)
Notch1 consists of three domains. The extracellular domain containing 36 epidermal growth factor (EGF) repeats and 3 lin-12/Notch repeats (LNR) and functions as a receptor in cell-cell interactions. There is a single transmembrane domain (TM). The intracellular domain contains six cdc10/ankyrin repeats (cdc10) and the newly defined Notch cytokine response (NCR) region, which contains a putative bipartite NLS (nuclear localization signal).
Immunogen
Cdc10-NCR region of mouse Notch1 expressed as a GST fusion protein.
Application
Anti-Notch 1 Antibody, clone mN1A is a high quality Mouse Monoclonal Antibody for the detection of Notch 1 & has been validated in ICC, IHC, IP & WB.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors
Transcription Factors
Western blot using ECL
Immunohistochemistry
Immunocytochemistry
Immunoprecipitation
Optimal working dilutions must be determined by the end user.
Immunohistochemistry
Immunocytochemistry
Immunoprecipitation
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
Recognizes Notch1, intracellular domain. The antibody has a high affinity for the "activated" intracellular form of Notch1, but a low affinity for the full-length (unprocessed or heterodimeric cell surface) forms. No reactivity with Notch2, 3 or 4.
Physical form
Format: Purified
Protein A purified
Purified immunoglobulin. Liquid.
Preparation Note
Maintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Analysis Note
Control
In fetal tissues, use spleen, brain stem and lung. In most adult tissues, use lymphoid tissues.
In fetal tissues, use spleen, brain stem and lung. In most adult tissues, use lymphoid tissues.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: 04-1046
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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저장 등급
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
시험 성적서(COA)
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