수량	카탈로그 번호	주문 설명	포장 단위	기재 가격
			96-Well Plate

수량	카탈로그 번호	주문 설명	포장 단위	기재 가격
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

444105 Sigma-AldrichAnti-Mannose 6-Phosphate Receptor Mouse mAb (2G11)

This Anti-Mannose 6-Phosphate Receptor Mouse mAb (2G11) is validated for use in Immunoblotting, IF, IHC, IP for the detection of Mannose 6-Phosphate Receptor.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

SDS
CoA
References
Data Sheet

Recommended Products

개요

Replacement Information

주요 사양표

Species Reactivity	Host	Antibody Type
B, H, Mk	M	Monoclonal Antibody

가격 및 재고여부

카탈로그 번호	재고 정보	패킹	포장 단위	가격(VAT 별도)	수량
444105-100UGCN	재고 정보 검색... — 현재 재고 없음 예상 출고 가능일 단종품 제한된 수량 가능 재고여부 확인 재고목록을 보려면 로그인하십시오 예상 출고 가능일 현재 재고 없음 예상 출고 가능일 Remaining: will advise Remaining: will advise 추천사항 고객 서비스로 문의 Contact Customer Service 고객 서비스로 문의 고객 서비스로 문의	Plastic ampoule	100 μg	가격 검색... 가격을 검색할 수 없습니다 Minimum Quantity needs to be mulitiple of Maximum Quantity is 가격 문의 추가 정보 ()이 할인됨 — 가격 문의 고객님의 가격을 보려면 로그인하십시오	재고 조회 —	즐겨찾기에 추가 즐겨찾기에 추가 나의 즐겨찾기에 추가

Description
Overview	Recognizes the ~300 kDa mannose 6-phosphate receptor protein.
Catalogue Number	444105
Brand Family	Calbiochem®

References
References	Dintzis, S., et al. 1994. J. Biol. Chem. 269, 12159. Dintzis, S., and Pfeffer, S. 1990. EMBO J. 9, 77.

Product Information
Form	Liquid
Formulation	In PBS.
Preservative	≤0.1% sodium azide
Quality Level	MQ100

Applications
Key Applications	Immunoblotting (Western Blotting) Immunofluorescence Immunohistochemistry Immunoprecipitation
Application Notes	Immunoblotting (1 µg/ml, non-reducing, see comments) Immunofluorescence (see comments) Immunohistochemistry (2-5 µg/ml) Immunoprecipitation (see comments)
Application Comments	Does not detect MPR in hamster (CHO) cells. Not suitable for immunoblotting using reducing conditions. This antibody has also been reported to work for immunoprecipitation and immunofluorescence. Variables associated with assay conditions will dictate the proper working dilution.

Biological Information
Immunogen	native bovine cation independent (CI)-mannose 6-phosphate receptor
Immunogen	Bovine
Epitope	within the extracelluar domain
Clone	2G11
Host	Mouse
Isotype	IgG_2a
Species Reactivity	Bovine Human Monkey
Antibody Type	Monoclonal Antibody
Concentration Label	Please refer to vial label for lot-specific concentration

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Dry Ice Only
Toxicity	Standard Handling
Storage	-20°C
Avoid freeze/thaw	Avoid freeze/thaw
Do not freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-20°C).

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
카탈로그 번호	GTIN
444105-100UGCN	04055977205411

Documentation

Anti-Mannose 6-Phosphate Receptor Mouse mAb (2G11) MSDS

타이틀
물질안전보건자료(MSDS)

Anti-Mannose 6-Phosphate Receptor Mouse mAb (2G11) Certificates of Analysis

Title	Lot Number
444105	로트(lot) 번호를 입력하십시오.

References

참고문헌 보기
Dintzis, S., et al. 1994. J. Biol. Chem. 269, 12159. Dintzis, S., and Pfeffer, S. 1990. EMBO J. 9, 77.

Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	07-August-2007 RFH
Application	Immunoblotting (1 µg/ml, non-reducing, see comments) Immunofluorescence (see comments) Immunohistochemistry (2-5 µg/ml) Immunoprecipitation (see comments)
Description	Purified mouse monoclonal antibody. Recognizes the mannose 6-phosphate receptor protein.
Background	Lysosomal enzymes containing one or two mannose 6-phosphate (man6P) moieties are moved about in the cell by two distinct but interconnected cycles by means of ~300 kDa cation-independent MPRs. The biosynthetic cycle refers to the MPR transport of newly synthesized lysosomal enzymes from the trans Golgi network to late endosomes or early lysosomes. The endocytic cycle transports extracellular lysosomal enzymes from the plasma membrane via clathrin-coated vesicles to early endosomes. The entire pool of MPRs cycles between these cellular compartments every 3 hours. The steady state distribution of MPRs is predominantly late endosomes, fewer in the trans Golgi network, and ~10% at cell surface. In addition to its man6P binding activity, MPR contains a separate binding site for the type II insulin-like growth factor and is capable of binding both man6P and IGF-II simultaneously. An ~240 kDa soluble, truncated form of the extracellular domain of MPR has been detected circulating in serum that is capable of binding both ligands.
Host	Mouse
Immunogen species	Bovine
Immunogen	native bovine cation independent (CI)-mannose 6-phosphate receptor
Epitope	within the extracelluar domain
Clone	2G11
Isotype	IgG_2a
Species	bovine, not hamster, human, monkey
Form	Liquid
Formulation	In PBS.
Concentration Label	Please refer to vial label for lot-specific concentration
Preservative	≤0.1% sodium azide
Comments	Does not detect MPR in hamster (CHO) cells. Not suitable for immunoblotting using reducing conditions. This antibody has also been reported to work for immunoprecipitation and immunofluorescence. Variables associated with assay conditions will dictate the proper working dilution.
Storage	Avoid freeze/thaw -20°C
Do Not Freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-20°C).
Toxicity	Standard Handling
References	Dintzis, S., et al. 1994. J. Biol. Chem. 269, 12159. Dintzis, S., and Pfeffer, S. 1990. EMBO J. 9, 77.

카테고리

Life Science Research > Antibodies and Assays > Primary Antibodies

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